Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | SYK | P43405 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | CASP6 | P55212 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9853650 | 0.92 | RAPGEF4 (0.38) | ALDH1A1SMN1; SMN2RAPGEF4MAPTSYK | |
| SCHEMBL9878800 | 0.86 | RAPGEF4 (0.38) | ALDH1A1RAPGEF4MAPTKDM4EPOLB | |
| SCHEMBL10576785 | 0.82 | RAPGEF4 (0.55) | CYP19A1ALDH1A1SMN1; SMN2RAPGEF4MAPT | |
| SCHEMBL9877841 | 0.81 | L3MBTL1 (0.45) | ALDH1A1MAPTKDM4EPOLBGAA | |
| SCHEMBL9877903 | 0.80 | ALDH1A1 (0.59) | CYP19A1ALDH1A1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL9879136 | 0.80 | CYP19A1 (0.42) | CYP19A1ALDH1A1SMN1; SMN2RAPGEF4MAPT | |
| SCHEMBL9350920 | 0.77 | RAPGEF4 (0.42) | ALDH1A1RAPGEF4MAPTKDM4EPOLB | |
| SCHEMBL9878469 | 0.77 | KMT2A (0.42) | ALDH1A1SMN1; SMN2MAPTSYKKDM4E | |
| SCHEMBL9878782 | 0.76 | RAPGEF4 (0.41) | ALDH1A1RAPGEF4MAPTKDM4EPOLB | |
| SCHEMBL17774691 | 0.74 | POLB (0.41) | ALDH1A1RAPGEF4MAPTKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992589-A | Substituted phenyl hydroxyethyl sulfones, and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-02-12 | — | — | US | disclosed |