Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.38 |
| ▸ | CASP6 | P55212 | 3/20 | 0.38 |
| ▸ | RECQL | P46063 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 2/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9879146 | 0.92 | CYP19A1 (0.40) | RAPGEF4KDM4EALDH1A1GAAMAPT | |
| SCHEMBL9878800 | 0.89 | RAPGEF4 (0.38) | RAPGEF4KDM4EALDH1A1GAAMAPT | |
| SCHEMBL9877841 | 0.83 | L3MBTL1 (0.45) | KDM4EALDH1A1GAAMAPTL3MBTL1 | |
| SCHEMBL10536585 | 0.81 | RAPGEF4 (0.43) | RAPGEF4KDM4EALDH1A1GAAMAPT | |
| SCHEMBL6578153 | 0.81 | RAPGEF4 (0.58) | RAPGEF4KDM4EALDH1A1GAAMAPT | |
| SCHEMBL9350920 | 0.80 | RAPGEF4 (0.42) | RAPGEF4KDM4EALDH1A1GAAMAPT | |
| SCHEMBL9877927 | 0.79 | KMT2A (0.54) | KDM4EALDH1A1GAAMAPTRECQL | |
| SCHEMBL9878469 | 0.79 | KMT2A (0.42) | KDM4EALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL8164756 | 0.78 | CA2 (0.43) | RAPGEF4KDM4EALDH1A1GAAMAPT | |
| SCHEMBL9878782 | 0.78 | RAPGEF4 (0.41) | RAPGEF4KDM4EALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0431389-A2 | Azo dyes and process for the manufacture of [5-amino-2-(2-hydroxyethylamino)phenyl](2-hydroxyethyl)sulfone | BAYER AG (DE) | 1991-06-12 | — | — | EP | disclosed |
| US-4992589-A | Substituted phenyl hydroxyethyl sulfones, and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-02-12 | — | — | US | disclosed |