Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | SI | P14410 | 2/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9527594 | 0.94 | CCR2 (0.35) | SLC6A4KDM2BMGAMGAASI | |
| SCHEMBL9528162 | 0.89 | CCR2 (0.35) | SLC6A4MGAMGAASIMGAM2 | |
| SCHEMBL9527469 | 0.85 | NPC1 (0.35) | SLC6A4KDM2BNPC1RAB9ATSHR | |
| SCHEMBL9526819 | 0.84 | CCR2 (0.33) | SLC6A4KDM2BMGAMGAASI | |
| SCHEMBL9527072 | 0.84 | B3GAT3 (0.34) | KDM2BGPR84HTR1A | |
| SCHEMBL9527895 | 0.83 | HTR7 (0.34) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL9526686 | 0.81 | NPC1 (0.36) | SLC6A4NPC1RAB9ATSHRHTT | |
| SCHEMBL9526603 | 0.79 | CCR2 (0.34) | MGAMGAASIMGAM2GPR84 | |
| SCHEMBL9527749 | 0.79 | HTR1D (0.35) | SLC6A4KDM2BRAB9A | |
| SCHEMBL9527712 | 0.77 | NPC1 (0.35) | KDM2BNPC1RAB9ATSHRFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5047402-A | Leukotriene Antagonists | ICI AMERICAS INC. (US) | 1991-09-10 | — | — | US | disclosed |