Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 4/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 7/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | WNK1 | Q9H4A3 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29516580 | 1.00 | PKM (0.67) | PKMALDH1A1TSHRTDP1MAPT | |
| SCHEMBL18116062 | 0.92 | MAPT (0.59) | PKMALDH1A1TSHRTDP1MAPT | |
| SCHEMBL1958428 | 0.87 | MAPT (0.71) | PKMALDH1A1TSHRTDP1MAPT | |
| SCHEMBL10422426 | 0.87 | MAPT (0.56) | PKMALDH1A1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL10485197 | 0.87 | PKM (0.65) | PKMALDH1A1TSHRTDP1MAPT | |
| SCHEMBL9877924 | 0.86 | PKM (0.64) | PKMALDH1A1TSHRTDP1MAPT | |
| SCHEMBL10595984 | 0.84 | LMNA (0.51) | PKMALDH1A1TDP1MAPTPOLB | |
| SCHEMBL5455310 | 0.83 | MAPT (0.70) | PKMALDH1A1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL18116066 | 0.81 | LMNA (0.53) | PKMALDH1A1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL8053888 | 0.80 | ALDH1A1 (0.63) | PKMALDH1A1TSHRTDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 348 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7799092-B2 | Composition for simultaneously bleaching and dyeing keratin fibers, comprising at least one anionic or nonionic direct dye and at least one associative polymer | L'OREAL S.A. (FR) | 2010-09-21 | — | — | US | claimed |
| US-7736395-B2 | direct dyes | L'OREAL S.A. (FR) | 2010-06-15 | — | — | US | claimed |
| EP-1738800-B1 | Agent for simultaneously bleaching and coloring of keratin fibres comprising an anionic or non-ionic dye and an asociative polymer | OREAL (FR) | 2010-06-09 | — | — | EP | claimed |
| EP-1738801-B1 | Agent for simultaneously bleaching and coloring of keratin fibres comprising an anionic or non-ionic dye and an inert organic liquid | OREAL (FR) | 2010-06-09 | — | — | EP | claimed |
| US-20070033744-A1 | Anhydrous composition; nonionic or anionic direct dye, associative polymer, peroxygenated salt, and alkaline agent; hair dyes suitable for dark hair; easy to use and can produce chromatic and fast coloration | L'OREAL S.A. (FR) | 2007-02-15 | — | — | US | claimed |
| US-20070033743-A1 | direct dyes | L'OREAL S.A. (FR) | 2007-02-15 | — | — | US | claimed |
| CN-1903161-A | Composition for simultaneously bleaching and coloring of keratin fibres comprising an anionic or non-ionic dye and an asociative polymer | OREAL (FR) | 2007-01-31 | — | — | CN | claimed |
| US-20050183212-A1 | Compositions for dyeing keratin fibers, comprising at least one alcohol oxidase and at least one direct dye comprising an acid functional group, or a salt thereof, and processes using these compositions | L'OREAL S.A. (FR) | 2005-08-25 | — | — | US | claimed |
| EP-0646108-B1 | HYDROXYPROPYLATED 2-NITRO-P-PHENYLENEDIAMINES, PREPARATION METHOD THEREFOR AND USE THEREOF FOR DYEING KERATIN FIBRES | OREAL (FR) | 1998-10-14 | — | — | EP | claimed |
| US-5792221-A | DYEING GRAY TO WHITE HAIR BLUE THROUGH PURPLISH-BLUE SHADES; WATER SOLUBILITY; WASH- AND COLORFASTNESS; WEATHERPROOFING; SWEAT RESISTANCE | L'OREAL (FR) | 1998-08-11 | — | — | US | claimed |
| EP-0646109-B1 | NOVEL HYDROXYETHYLATED 2-NITRO-P-PHENYLENEDIAMINES AND USE THEREOF FOR DYEING KERATIN FIBRES | OREAL (FR) | 1997-09-03 | — | — | EP | claimed |
| EP-0673926-B1 | 2-Nitro-p-phenylenediamines having a sulfur atom in position 5, process for their preparation, dye compositions containing them and their use for dyeing keratinic fibres | OREAL (FR) | 1997-04-09 | — | — | EP | claimed |
| US-5516942-A | DIRECT DYES FOR HAIR FOR YELLOW OR PURPLE | L'OREAL (FR) | 1996-05-14 | — | — | US | claimed |
| CN-120035427-A | Composition for lightening keratin fibres and method for lightening keratin fibres using said composition | 莱雅公司 | 2025-05-23 | — | — | CN | disclosed |
| CN-119968189-A | Composition for lightening keratin fibres and method for lightening keratin fibres using said composition | 莱雅公司 | 2025-05-09 | — | — | CN | disclosed |
| CN-119894486-A | Composition for lightening keratin fibres and method for lightening keratin fibres using said composition | 莱雅公司 | 2025-04-25 | — | — | CN | disclosed |
| US-5792221-A | DYEING GRAY TO WHITE HAIR BLUE THROUGH PURPLISH-BLUE SHADES; WATER SOLUBILITY; WASH- AND COLORFASTNESS; WEATHERPROOFING; SWEAT RESISTANCE | L'OREAL (FR) | 1998-08-11 | — | — | US | disclosed |
| US-5735910-A | DIRECT HAIR DYES; WASHFASTNESS, COLORFASTNESS | L'OREAL (FR) | 1998-04-07 | — | — | US | disclosed |
| US-5516942-A | DIRECT DYES FOR HAIR FOR YELLOW OR PURPLE | L'OREAL (FR) | 1996-05-14 | — | — | US | disclosed |
| US-4619666-A | Hair dyes containing amino-nitrobenzoic acid or amino-nitrobenzene sulfonic acids as substantive dyes | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1986-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070033744-A1 | Anhydrous composition; nonionic or anionic direct dye, associative polymer, peroxygenated salt, and alkaline agent; hair dyes suitable for dark hair; easy to use and can produce chromatic and fast coloration | KRT18, BRD7, KAT7 | PKM 1394/4885ALDH1A1 930/4885TSHR 3126/4885 |
| US-20070033743-A1 | direct dyes | KRT18, DSG1, DSP | PKM 1116/4885ALDH1A1 385/4885TSHR 4673/4885 |
| US-20050183212-A1 | Compositions for dyeing keratin fibers, comprising at least one alcohol oxidase and at least one direct dye comprising an acid functional group, or a salt thereof, and processes using these compositions | KRT18, ADH5, ADH1C | PKM 785/4885ALDH1A1 20/4885TSHR 4665/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.