Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.43 |
| ▸ | PIM1 | P11309 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | STAT1 | P42224 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9877954 | 1.00 | MAPT (0.53) | MAPTKDM4EALDH1A1HPGDMAPK1 | |
| SCHEMBL9877172 | 0.83 | NTRK1 (0.64) | MAPTKDM4EALDH1A1NTRK1PIM1 | |
| SCHEMBL9877170 | 0.83 | NTRK1 (0.64) | MAPTKDM4EALDH1A1NTRK1PIM1 | |
| SCHEMBL9728729 | 0.76 | NTRK1 (0.53) | MAPTKDM4EALDH1A1NTRK1PIM1 | |
| SCHEMBL9878320 | 0.72 | KDM4E (0.48) | KDM4ENTRK1PIM1CHEK1CDK2 | |
| SCHEMBL9728647 | 0.72 | KDM4E (0.48) | KDM4ENTRK1PIM1CHEK1CDK2 | |
| SCHEMBL9877259 | 0.69 | NTRK1 (0.43) | MAPTMAPK1NTRK1PIM1NPC1 | |
| SCHEMBL9728952 | 0.69 | KDM4E (1.00) | MAPTKDM4EALDH1A1HPGDMAPK1 | |
| SCHEMBL28008033 | 0.66 | MEN1 (0.49) | MAPTKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL9728973 | 0.65 | CLK4 (0.61) | KDM4EALDH1A1HPGDNTRK1PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5059691-A | Anxiolytic agents; hypotensive agents; nervous system disorders; cognition activators | AMERICAN CYANAMID COMPANY (US) | 1991-10-22 | — | — | US | claimed |