Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 6/20 | 0.42 |
| ▸ | MAOB | P27338 | 6/20 | 0.42 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.40 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14493279 | 0.81 | ALDH1A1 (0.42) | ALDH1A1MAPK1TDP1HPGDCYP3A4 | |
| SCHEMBL8484820 | 0.79 | LIMK1 (0.52) | MAOAMAOBLIMK1LIMK2ALDH1A1 | |
| SCHEMBL9473535 | 0.78 | ALDH1A1 (0.42) | ALDH1A1MAPK1HPGDMEN1MAPT | |
| SCHEMBL12650288 | 0.78 | ALDH1A1 (0.53) | ALDH1A1MAPK1TDP1HPGDLMNA | |
| SCHEMBL8673185 | 0.78 | HSD11B1 (0.51) | ALDH1A1TDP1LMNATSHRKDM4E | |
| SCHEMBL10296224 | 0.78 | GSK3B (0.45) | ALDH1A1MAPK1TDP1HPGDCYP3A4 | |
| SCHEMBL15453504 | 0.76 | MAOA (0.51) | MAOAMAOBALDH1A1HPGDCYP3A4 | |
| SCHEMBL9877666 | 0.76 | ALDH1A1 (0.44) | ALDH1A1HPGDCYP3A4LMNAKDM4E | |
| SCHEMBL28381203 | 0.75 | ADRA2C (0.54) | MAOAMAOBALDH1A1TDP1HPGD | |
| SCHEMBL14855616 | 0.75 | HPGD (0.46) | ALDH1A1MAPK1TDP1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5036098-A | Urogenital disorders | NIPPON SHINYAKU CO., LTD. (JP) | 1991-07-30 | — | — | US | disclosed |