Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9877543 | 0.84 | RAB9A (0.44) | ALDH1A1MAPTHTTRAB9AGAA | |
| SCHEMBL6397529 | 0.79 | DPP8 (0.54) | ALDH1A1MAPTHTTRAB9AGAA | |
| SCHEMBL9878069 | 0.77 | RAB9A (0.46) | ALDH1A1MAPTHTTRAB9AGAA | |
| SCHEMBL9878441 | 0.77 | HTT (0.43) | ALDH1A1MAPTHTTRAB9AGAA | |
| SCHEMBL11253472 | 0.75 | IDO1 (0.43) | ALDH1A1MAPTHTTRAB9AGAA | |
| SCHEMBL10402671 | 0.73 | IDO1 (0.53) | ALDH1A1MAPTHTTRAB9AGAA | |
| SCHEMBL9877402 | 0.73 | TGM2 (0.44) | ALDH1A1MAPTHTTRAB9AGAA | |
| SCHEMBL8849150 | 0.73 | IDO1 (0.56) | ALDH1A1MAPTHTTRAB9APOLB | |
| SCHEMBL8849145 | 0.73 | IDO1 (0.56) | ALDH1A1MAPTHTTRAB9APOLB | |
| SCHEMBL9878050 | 0.73 | ALDH1A1 (0.45) | ALDH1A1MAPTHTTRAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992542-A | Thienamycin antibiotics | MERCK & CO., INC. (US) | 1991-02-12 | — | — | US | disclosed |