Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.44 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9877543 | 0.93 | RAB9A (0.44) | RAB9ADPP8DPP9IDO1ALDH1A1 | |
| SCHEMBL9877881 | 0.90 | RAB9A (0.46) | RAB9ADPP8DPP9TGM2IDO1 | |
| SCHEMBL9878619 | 0.88 | RAB9A (0.45) | RAB9ADPP8DPP9TGM2IDO1 | |
| SCHEMBL6397257 | 0.82 | DPP8 (0.57) | RAB9ADPP8DPP9TGM2IDO1 | |
| SCHEMBL9878155 | 0.81 | RAB9A (0.48) | RAB9ADPP8DPP9ALDH1A1MAPT | |
| SCHEMBL11160866 | 0.79 | RAB9A (0.46) | RAB9AIDO1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL10756101 | 0.78 | DPP8 (0.59) | RAB9ADPP8DPP9TGM2ALDH1A1 | |
| SCHEMBL9878052 | 0.77 | ALDH1A1 (0.43) | RAB9AALDH1A1MAPTHTTGAA | |
| SCHEMBL9574265 | 0.77 | DPP8 (0.40) | RAB9ADPP8DPP9ALDH1A1MAPT | |
| SCHEMBL9574263 | 0.77 | MAPT (0.40) | RAB9ADPP8DPP9ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992542-A | Thienamycin antibiotics | MERCK & CO., INC. (US) | 1991-02-12 | — | — | US | disclosed |