Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11100083 | 0.85 | DPP8 (0.52) | RAB9ASMN1; SMN2NPC1MAPTHTT | |
| SCHEMBL9877881 | 0.82 | RAB9A (0.46) | RAB9ASMN1; SMN2NPC1MAPTHTT | |
| SCHEMBL9878069 | 0.81 | RAB9A (0.46) | RAB9ASMN1; SMN2NPC1MAPTHTT | |
| SCHEMBL9878619 | 0.81 | RAB9A (0.45) | RAB9ASMN1; SMN2MAPTHTTL3MBTL1 | |
| SCHEMBL9877543 | 0.79 | RAB9A (0.44) | RAB9ASMN1; SMN2NPC1MAPTHTT | |
| SCHEMBL9877425 | 0.78 | RAB9A (0.53) | RAB9ASMN1; SMN2NPC1MAPTHTT | |
| SCHEMBL11160866 | 0.72 | RAB9A (0.46) | RAB9ASMN1; SMN2NPC1MAPTALDH1A1 | |
| SCHEMBL11514795 | 0.72 | RAB9A (0.65) | RAB9ASMN1; SMN2MAPTL3MBTL1ALDH1A1 | |
| SCHEMBL9574265 | 0.71 | DPP8 (0.40) | RAB9ANPC1MAPTALDH1A1GAA | |
| SCHEMBL9574263 | 0.70 | MAPT (0.40) | RAB9ASMN1; SMN2NPC1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992542-A | Thienamycin antibiotics | MERCK & CO., INC. (US) | 1991-02-12 | — | — | US | disclosed |