Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.43 |
| ▸ | TGM2 | P21980 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9877881 | 0.89 | RAB9A (0.46) | RAB9ADPP8DPP9TGM2IDO1 | |
| SCHEMBL9878069 | 0.88 | RAB9A (0.46) | RAB9ADPP8DPP9TGM2IDO1 | |
| SCHEMBL9877543 | 0.85 | RAB9A (0.44) | RAB9ADPP8DPP9IDO1ALDH1A1 | |
| SCHEMBL11099186 | 0.82 | DPP8 (0.56) | RAB9ADPP8DPP9TGM2ALDH1A1 | |
| SCHEMBL9878155 | 0.81 | RAB9A (0.48) | RAB9ADPP8DPP9ALDH1A1MAPT | |
| SCHEMBL9878441 | 0.79 | HTT (0.43) | RAB9ADPP8DPP9TGM2IDO1 | |
| SCHEMBL11160866 | 0.78 | RAB9A (0.46) | RAB9AIDO1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9878438 | 0.78 | RAB9A (0.42) | RAB9AIDO1ALDH1A1MAPTPOLB | |
| SCHEMBL9878075 | 0.76 | DPP8 (0.54) | RAB9ADPP8DPP9TGM2IDO1 | |
| SCHEMBL9574265 | 0.74 | DPP8 (0.40) | RAB9ADPP8DPP9ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992542-A | Thienamycin antibiotics | MERCK & CO., INC. (US) | 1991-02-12 | — | — | US | disclosed |