Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.34 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22715296 | 0.79 | CSNK2A2 (0.44) | HTTL3MBTL1KDM4EMAPTKMT2A | |
| SCHEMBL6033604 | 0.79 | HTT (0.46) | HTTL3MBTL1KDM4EMAPTKMT2A | |
| SCHEMBL9879081 | 0.74 | HTT (0.49) | HTTL3MBTL1KDM4EMAPTPKM | |
| SCHEMBL9879418 | 0.74 | HTT (0.45) | HTTL3MBTL1KDM4EPKMALDH1A1 | |
| SCHEMBL9879042 | 0.72 | HTT (0.40) | HTTL3MBTL1KDM4EMAPTPKM | |
| SCHEMBL172129 | 0.72 | ALDH1A1 (0.37) | L3MBTL1KDM4EMAPTALDH1A1HPGD | |
| SCHEMBL9829434 | 0.71 | XDH (0.49) | L3MBTL1KDM4EMAPTALDH1A1XDH | |
| SCHEMBL10870262 | 0.70 | HTT (0.38) | HTTL3MBTL1KDM4EMAPTPKM | |
| SCHEMBL10870260 | 0.70 | HTT (0.38) | HTTL3MBTL1KDM4EMAPTPKM | |
| SCHEMBL9879120 | 0.70 | HTT (0.63) | HTTL3MBTL1KDM4EMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991018887-A1 | DIAMINOPYRIMIDINE COMPOUNDS | SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) | 1991-12-12 | — | — | WO | disclosed |