Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.45 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11079720 | 0.74 | POLB (0.56) | ALDH1A1KDM4EL3MBTL1HPGDLMNA | |
| SCHEMBL9879119 | 0.71 | HTT (0.48) | XDHALDH1A1KDM4EL3MBTL1HPGD | |
| SCHEMBL7769423 | 0.69 | KDM4E (0.69) | XDHALDH1A1KDM4EL3MBTL1HPGD | |
| SCHEMBL26039905 | 0.69 | ALDH1A1 (0.70) | XDHALDH1A1LMNAPOLBGAA | |
| SCHEMBL8407246 | 0.69 | ALDH1A1 (0.50) | XDHALDH1A1KDM4EL3MBTL1HPGD | |
| SCHEMBL1132916 | 0.68 | ALDH1A1 (0.44) | XDHALDH1A1KDM4EL3MBTL1HPGD | |
| SCHEMBL9879442 | 0.67 | ALDH1A1 (0.74) | ALDH1A1L3MBTL1LMNAPOLBMAPT | |
| SCHEMBL1902297 | 0.66 | XDH (0.47) | XDHALDH1A1KDM4EL3MBTL1HPGD | |
| SCHEMBL3382433 | 0.66 | KDM4E (1.00) | ALDH1A1KDM4EL3MBTL1HPGDLMNA | |
| SCHEMBL10631883 | 0.65 | PARP1 (0.51) | XDHALDH1A1KDM4EL3MBTL1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0422178-A1 | PYRIMIDINE DERIVATIVES. | ICI PLC (GB) | 1991-04-17 | — | — | EP | disclosed |