Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PNP | P00491 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | TYMP | P19971 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CDK4 | P11802 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9878825 | 0.76 | HTT (0.70) | XDHL3MBTL1SMN1; SMN2HTTKMT2A | |
| SCHEMBL9879126 | 0.71 | L3MBTL1 (0.46) | TYMSXDHL3MBTL1NPSR1MAPK1 | |
| SCHEMBL718210 | 0.70 | NPSR1 (0.52) | XDHL3MBTL1NPSR1MAPK1PNP | |
| SCHEMBL12956972 | 0.70 | CDK1 (0.52) | TYMSXDHL3MBTL1NPSR1PNP | |
| SCHEMBL2343355 | 0.68 | PNP (0.59) | PNPKMT2AMAPT | |
| SCHEMBL18294954 | 0.67 | SMN1; SMN2 (0.55) | L3MBTL1MAPK1SMN1; SMN2HTTCYP1A2 | |
| SCHEMBL9879338 | 0.67 | HSP90AA1 (0.38) | L3MBTL1NPSR1SMN1; SMN2CYP1A2KMT2A | |
| SCHEMBL9878974 | 0.67 | MEN1 (0.51) | MAPK1KMT2AMAPT | |
| SCHEMBL10618579 | 0.65 | NOS1 (0.68) | KMT2AMAPT | |
| SCHEMBL22354697 | 0.64 | ALDH1A1 (0.43) | TYMSXDHNPSR1MAPK1PNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991018887-A1 | DIAMINOPYRIMIDINE COMPOUNDS | SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) | 1991-12-12 | — | — | WO | disclosed |