Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 1/20 | 0.52 |
| ▸ | CDK4 | P11802 | 1/20 | 0.52 |
| ▸ | CDK2 | P24941 | 1/20 | 0.52 |
| ▸ | XDH | P47989 | 1/20 | 0.52 |
| ▸ | PNP | P00491 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | TYMP | P19971 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HBB | P68871 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | QTRT1 | Q9BXR0 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TYMS | P04818 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL718210 | 0.81 | NPSR1 (0.52) | CDK1CDK4CDK2XDHPNP | |
| SCHEMBL1271646 | 0.75 | CDK1 (0.56) | CDK1CDK4CDK2PNPMAPT | |
| SCHEMBL8201950 | 0.74 | XDH (0.46) | CDK1CDK4CDK2XDHPNP | |
| SCHEMBL19506131 | 0.74 | XDH (0.46) | CDK1CDK4CDK2XDHPNP | |
| Hydrochloric Acid SCHEMBL12474436 | 0.73 | CDK1 (0.54) | CDK1CDK4CDK2PNPMAPT | |
| SCHEMBL7167384 | 0.73 | CDK1 (0.54) | CDK1CDK4CDK2XDHPNP | |
| SCHEMBL12284639 | 0.71 | ALDH1A1 (0.65) | CDK1CDK4CDK2XDHPNP | |
| SCHEMBL3180710 | 0.71 | CDK1 (0.52) | CDK1CDK4CDK2PNPMAPT | |
| SCHEMBL9879130 | 0.70 | TYMS (0.43) | CDK1CDK4CDK2XDHPNP | |
| SCHEMBL22354697 | 0.70 | ALDH1A1 (0.43) | XDHPNPNPSR1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190225644-A1 | MRNA CAP ANALOGS AND METHODS OF MRNA CAPPING | MODERNATX, INC. | 2019-07-25 | — | — | US | disclosed |
| US-20140323726-A1 | Methods for synthesizing molybdopterin precursor Z derivatives | ALEXION PHARMA INTERNATIONAL SÀRL (CH) | 2014-10-30 | — | — | US | disclosed |
| EP-1644389-B1 | PYRIMIDINE COMPOUNDS HAVING PHOSPHONATE GROUPS AS ANTIVIRAL NUCLEOTIDE ANALOGS | ACAD OF SCIENCE CZECH REPUBLIC (CZ) | 2011-01-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140323726-A1 | Methods for synthesizing molybdopterin precursor Z derivatives | MTHFD2, ADH1B, DPYD | CDK1 1853/4885CDK4 2687/4885CDK2 1427/4885 |
| US-20190225644-A1 | MRNA CAP ANALOGS AND METHODS OF MRNA CAPPING | RNGTT, RNMT, NSUN2 | CDK1 3280/4885CDK4 3989/4885CDK2 3299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.