Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.32 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 3/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9211995 | 0.90 | GRIA2 (0.32) | P2RX7GAASLC6A2SLC6A4CYP1A2 | |
| SCHEMBL9212819 | 0.89 | NR1H4 (0.35) | P2RX7GAANAMPTHSD17B10ALDH1A1 | |
| SCHEMBL9212243 | 0.89 | NAMPT (0.38) | P2RX7ITGA4ITGB7SMN1; SMN2NAMPT | |
| SCHEMBL9219311 | 0.86 | EPHX2 (0.38) | NAMPTALDH1A1TSHR | |
| SCHEMBL9216670 | 0.83 | P2RX7 (0.33) | P2RX7GAASLC6A2SLC6A4ITGA4 | |
| SCHEMBL9209965 | 0.82 | GAA (0.35) | P2RX7GAASLC6A2SLC6A4ITGA4 | |
| SCHEMBL9217244 | 0.82 | GAA (0.35) | P2RX7GAASLC6A2SLC6A4ITGA4 | |
| SCHEMBL9214348 | 0.81 | GAA (0.33) | P2RX7GAASLC6A2SLC6A4SMN1; SMN2 | |
| SCHEMBL9214996 | 0.80 | ITGB3 (0.33) | P2RX7GAASLC6A2SLC6A4SMN1; SMN2 | |
| SCHEMBL9217629 | 0.79 | SLC1A3 (0.36) | SMN1; SMN2NAMPTHSD17B10ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0510028-B1 | THIOFORMAMIDE DERIVATIVES | RHONE POULENC RORER SA (FR) | 1995-03-15 | — | — | EP | claimed |