SCHEMBL9889203

SCHEMBL9889203

CC1(C)OC(=O)C(=C/C=C/N(CC(=O)OCc2ccccc2)CC(=O)OCc2ccccc2)C(=O)O1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.40
MAPK1 P28482 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
APP P05067 1/20 0.37
GAA P10253 1/20 0.36
PKM P14618 1/20 0.36
CDC25B P30305 1/20 0.36
GLA P06280 1/20 0.36
HCAR2 Q8TDS4 1/20 0.35
SLC6A2 P23975 1/20 0.35
SLC6A3 Q01959 1/20 0.35
KMT2A Q03164 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
LMNA P02545 2/20 0.34
MAPT P10636 1/20 0.34
HPGD P15428 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9892446 0.83 APP (0.39) ALDH1A1L3MBTL1APPGAAKMT2A
SCHEMBL9889263 0.76 APP (0.40) ALDH1A1L3MBTL1APPLMNASMN1; SMN2
SCHEMBL20434966 0.73 HCAR2 (0.50) ALDH1A1MAPK1L3MBTL1GAAPKM
SCHEMBL21128873 0.69 APP (0.43) ALDH1A1MAPK1L3MBTL1APPCDC25B
SCHEMBL12260839 0.69 ALDH1A1 (0.49) ALDH1A1MAPK1L3MBTL1APPKMT2A
SCHEMBL19726788 0.68 ALDH1A1 (0.61) ALDH1A1MAPK1L3MBTL1CDC25BHCAR2
SCHEMBL14586581 0.68 ALDH1A1 (0.61) ALDH1A1MAPK1L3MBTL1CDC25BHCAR2
SCHEMBL8377215 0.68 ALDH1A1 (0.61) ALDH1A1MAPK1L3MBTL1CDC25BHCAR2
SCHEMBL8377212 0.68 ALDH1A1 (0.61) ALDH1A1MAPK1L3MBTL1CDC25BHCAR2
SCHEMBL14330112 0.67 ALDH1A1 (0.40) ALDH1A1MAPK1L3MBTL1APPHCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8652364-B2 Polymer film, ultraviolet absorber, merocyanine compound and process for preparing merocyanine compound FUJIFILM CORPORATION (JP) 2014-02-18 US disclosed
US-8652364-B2 Polymer film, ultraviolet absorber, merocyanine compound and process for preparing merocyanine compound FUJIFILM CORPORATION (JP) 2014-02-18 US disclosed
US-20120140161-A1 POLYMER FILM, RETARDATION FILM, POLARIZING PLATE, LIQUID CRYSTAL DISPLAY DEVICE AND ULTRAVIOLET ABSORBER FUJIFILM CORPORATION (JP) 2012-06-07 US disclosed
US-20120140161-A1 POLYMER FILM, RETARDATION FILM, POLARIZING PLATE, LIQUID CRYSTAL DISPLAY DEVICE AND ULTRAVIOLET ABSORBER FUJIFILM CORPORATION (JP) 2012-06-07 US disclosed
US-20110220843-A1 POLYMER FILM, ULTRAVIOLET ABSORBER, MEROCYANINE COMPOUND AND PROCESS FOR PREPARING MEROCYANINE COMPOUND FUJIFILM CORPORATION (JP) 2011-09-15 US disclosed
US-20110220843-A1 POLYMER FILM, ULTRAVIOLET ABSORBER, MEROCYANINE COMPOUND AND PROCESS FOR PREPARING MEROCYANINE COMPOUND FUJIFILM CORPORATION (JP) 2011-09-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110220843-A1 POLYMER FILM, ULTRAVIOLET ABSORBER, MEROCYANINE COMPOUND AND PROCESS FOR PREPARING MEROCYANINE COMPOUND HAMP, CRY1, CRY2 ALDH1A1 1899/4885MAPK1 4142/4885L3MBTL1 3822/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.