SCHEMBL9889263

SCHEMBL9889263

CC(=O)CN(/C=C/C=C1C(=O)OC(C)(C)OC1=O)CC(C)=O

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.40
L3MBTL1 Q9Y468 3/20 0.35
ALDH1A1 P00352 10/20 0.34
KDM4E B2RXH2 1/20 0.33
CRHBP P24387 1/20 0.33
CRHR2 Q13324 1/20 0.33
CYP2C9 P11712 2/20 0.31
CYP1A2 P05177 2/20 0.31
LMNA P02545 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
CYP2C19 P33261 1/20 0.31
PTPN1 P18031 1/20 0.31
RAB9A P51151 1/20 0.31
CYP3A4 P08684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21128873 0.80 APP (0.43) APPL3MBTL1ALDH1A1CRHBPCRHR2
SCHEMBL12758237 0.79 APP (0.40) APPL3MBTL1ALDH1A1KDM4ECRHBP
SCHEMBL14456205 0.78 APP (0.41) APPL3MBTL1ALDH1A1CRHBPCRHR2
SCHEMBL9889234 0.77 APP (0.41) APPL3MBTL1ALDH1A1KDM4ESMN1; SMN2
SCHEMBL9892476 0.76 APP (0.37) APPL3MBTL1ALDH1A1CRHBPCRHR2
SCHEMBL9889203 0.76 ALDH1A1 (0.40) APPL3MBTL1ALDH1A1CYP2C9CYP1A2
SCHEMBL24416732 0.75 APP (0.40) APPL3MBTL1ALDH1A1CRHBPCRHR2
SCHEMBL9889241 0.74 APP (0.50) APPL3MBTL1ALDH1A1KDM4ECRHBP
SCHEMBL9889238 0.73 APP (0.44) APPALDH1A1CRHBPCRHR2CYP2C9
SCHEMBL12758232 0.73 PTPN1 (0.43) APPL3MBTL1ALDH1A1CRHBPCRHR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9110243-B2 Laminate film, optically compensatory film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2015-08-18 US disclosed
US-8652364-B2 Polymer film, ultraviolet absorber, merocyanine compound and process for preparing merocyanine compound FUJIFILM CORPORATION (JP) 2014-02-18 US disclosed
US-20120251781-A1 LAMINATE FILM, OPTICALLY COMPENSATORY FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-10-04 US disclosed
US-20120140161-A1 POLYMER FILM, RETARDATION FILM, POLARIZING PLATE, LIQUID CRYSTAL DISPLAY DEVICE AND ULTRAVIOLET ABSORBER FUJIFILM CORPORATION (JP) 2012-06-07 US disclosed
US-20110311738-A1 Process of producing cellulose acylate film, cellulose acylate film, polarizing plate liquid crystal display device and optical compensation film FUJIFILM CORPORATION (JP) 2011-12-22 US disclosed
US-20110229662-A1 Polymer film, production method for the film, and retardation film, polarizing plate and liquid-crystal display device having the film FUJIFILM CORPORATION (JP) 2011-09-22 US disclosed
US-20110220843-A1 POLYMER FILM, ULTRAVIOLET ABSORBER, MEROCYANINE COMPOUND AND PROCESS FOR PREPARING MEROCYANINE COMPOUND FUJIFILM CORPORATION (JP) 2011-09-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110220843-A1 POLYMER FILM, ULTRAVIOLET ABSORBER, MEROCYANINE COMPOUND AND PROCESS FOR PREPARING MEROCYANINE COMPOUND HAMP, CRY1, CRY2 APP 97/4885L3MBTL1 3822/4885ALDH1A1 1899/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.