Known targets — ChEMBL curated mechanism
ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | GRK2 | P25098 | 2/20 | 0.47 |
| ▸ | APAF1 | O14727 | 1/20 | 0.47 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.47 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.47 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.39 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.37 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL2103287 | 0.92 | POLB (0.49) | POLBL3MBTL1GRK2APAF1DNMT1 | |
| Sulfuric Acid SCHEMBL2913751 | 0.90 | POLB (0.47) | POLBL3MBTL1GRK2APAF1DNMT1 | |
| SCHEMBL28323005 | 0.88 | BBOX1 (0.52) | POLBL3MBTL1GRK2APAF1DNMT1 | |
| SCHEMBL989048 | 0.86 | DNM1 (0.46) | POLBL3MBTL1GRK2APAF1DNMT1 | |
| SCHEMBL1294496 | 0.84 | MEN1 (0.39) | POLBL3MBTL1GRK2APAF1DNMT1 | |
| Choline SCHEMBL15527809 | 0.84 | MEN1 (0.60) | POLBL3MBTL1GRK2APAF1DNMT1 | |
| SCHEMBL4611912 | 0.84 | DNM1 (0.74) | DNM1KMT2APSMD14PLA2G1BHSP90AA1 | |
| SCHEMBL2921089 | 0.83 | POLB (0.44) | POLBL3MBTL1GRK2APAF1DNMT1 | |
| Trifluoromethanesulfonic Acid SCHEMBL2921141 | 0.81 | POLB (0.46) | POLBL3MBTL1GRK2APAF1DNMT1 | |
| Sulfuric Acid SCHEMBL27753589 | 0.80 | BBOX1 (0.54) | POLBL3MBTL1GRK2APAF1DNMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893716-B1 | NOVEL WORKING MEDIA FOR REFRIGERATION PROCESSES | EVONIK DEGUSSA GMBH (DE) | 2016-07-13 | — | — | EP | claimed |
| US-20100095703-A1 | Novel Working Media for Refrigeration Processes | EVONIK DEGUSSA GMBH (DE) | 2010-04-22 | — | — | US | claimed |
| EP-1893716-A1 | NOVEL WORKING MEDIA FOR REFRIGERATION PROCESSES | Evonik Degussa GmbH (DE) | 2008-03-05 | — | — | EP | claimed |
| WO-2006134015-A1 | NOVEL WORKING MEDIA FOR REFRIGERATION PROCESSES | EVONIK DEGUSSA GMBH (DE) | 2006-12-21 | — | — | WO | claimed |
| US-12630663-B2 | Aqueous polyurethane resin dispersion | AGFA NV (BE) | 2026-05-19 | — | — | US | disclosed |
| EP-3717534-B1 | AQUEOUS POLYURETHANE RESIN DISPERSION | AGFA NV (BE) | 2024-05-08 | — | — | EP | disclosed |
| EP-4165097-B1 | AQUEOUS POLYURETHANE RESIN DISPERSION | AGFA NV (BE) | 2024-03-20 | — | — | EP | disclosed |
| US-11802205-B2 | Aqueous polyurethane resin dispersion | AGFA NV (BE) | 2023-10-31 | — | — | US | disclosed |
| US-20230220145-A1 | Aqueous Polyurethane Resin Dispersion | AGFA NV (BE) | 2023-07-13 | — | — | US | disclosed |
| EP-4165097-A1 | AQUEOUS POLYURETHANE RESIN DISPERSION | AGFA NV (BE) | 2023-04-19 | — | — | EP | disclosed |
| US-11585196-B2 | Methods of using energized well treating fluids | BAKER HUGHES OILFIELD OPERATIONS LLC (US) | 2023-02-21 | — | — | US | disclosed |
| CN-115667339-A | Aqueous polyurethane resin dispersion | 爱克发有限公司 | 2023-01-31 | — | — | CN | disclosed |
| US-20100016205-A1 | USE OF IONIC LIQUIDS AS AN ADDITIVE FOR CLEANING PROCESSES IN LIQUEFIED AND/OR SUPERCRITICAL GAS | EVONIK GOLDSCHMIDT GMBH (DE) | 2010-01-21 | — | — | US | disclosed |
| EP-2093278-A1 | Performance additive for improving the sprinkling characteristics of ionic fluids on solid surfaces | Evonik Goldschmidt GmbH (DE) | 2009-08-26 | — | — | EP | disclosed |
| WO-2009097930-A2 | METHOD FOR ABSORBING A VOLATILE SUBSTANCE IN A LIQUID ABSORPTION AGENT | EVONIK DEGUSSA GMBH (DE) | 2009-08-13 | — | — | WO | disclosed |
| EP-2087930-A1 | Method for the absorption of volatile material in a fluid absorption agent | Evonik Degussa GmbH (DE) | 2009-08-12 | — | — | EP | disclosed |
| EP-2087931-A2 | Defoaming of ionic fluids | Evonik Goldschmidt GmbH (DE) | 2009-08-12 | — | — | EP | disclosed |
| US-20090036334-A1 | USE OF IONIC LIQUIDS FOR THE LUBRICATION OF COMPONENTS IN WIND POWER PLANTS | EVONIK GOLDSCHMIDT GMBH (DE) | 2009-02-05 | — | — | US | disclosed |
| EP-1893716-A1 | NOVEL WORKING MEDIA FOR REFRIGERATION PROCESSES | Evonik Degussa GmbH (DE) | 2008-03-05 | — | — | EP | disclosed |
| WO-2006134015-A1 | NOVEL WORKING MEDIA FOR REFRIGERATION PROCESSES | EVONIK DEGUSSA GMBH (DE) | 2006-12-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12630663-B2 | Aqueous polyurethane resin dispersion | PUF60, PCMT1, EED | SLC6A4 2792/4885POLB 2839/4885L3MBTL1 769/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.