SCHEMBL9890922

SCHEMBL9890922

c1cc(-c2c3ccccc3c(-c3ccc4ccc5ccccc5c4c3)c3ccccc23)cc(-n2c3ccccc3c3ccccc32)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.44
KDM4E B2RXH2 1/20 0.44
ATM Q13315 1/20 0.44
ALDH1A1 P00352 4/20 0.39
HSD17B10 Q99714 3/20 0.39
HIF1A Q16665 1/20 0.39
CYP1B1 Q16678 1/20 0.39
KMT2A Q03164 3/20 0.35
TDP1 Q9NUW8 2/20 0.35
CYP2A6 P11509 1/20 0.35
TSHR P16473 1/20 0.35
CYP1A2 P05177 2/20 0.35
HPGD P15428 1/20 0.35
ALOX5 P09917 1/20 0.34
EDNRB P24530 1/20 0.33
EDNRA P25101 1/20 0.33
HPRT1 P00492 1/20 0.33
EGFR P00533 1/20 0.33
ERBB2 P04626 1/20 0.33
IL1R1 P14778 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17358423 0.92 L3MBTL1 (0.48) L3MBTL1KDM4EATMALDH1A1HSD17B10
SCHEMBL17358413 0.91 L3MBTL1 (0.47) L3MBTL1KDM4EATMALDH1A1HSD17B10
SCHEMBL124870 0.90 KDM4E (0.46) L3MBTL1KDM4EATMKMT2AALOX5
SCHEMBL12571717 0.89 KDM4E (0.42) L3MBTL1KDM4EATMCYP1B1KMT2A
SCHEMBL17718055 0.89 KDM4E (0.42) L3MBTL1KDM4EATMALDH1A1HSD17B10
SCHEMBL17358429 0.88 KDM4E (0.44) L3MBTL1KDM4EATMALDH1A1HSD17B10
SCHEMBL9890883 0.88 KDM4E (0.47) L3MBTL1KDM4EATMALDH1A1HSD17B10
SCHEMBL14947902 0.87 L3MBTL1 (0.57) L3MBTL1KDM4EATMALDH1A1HSD17B10
SCHEMBL22146173 0.87 ATM (0.45) L3MBTL1KDM4EATMALDH1A1HSD17B10
SCHEMBL12400929 0.87 KDM4E (0.43) L3MBTL1KDM4EATMALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8502201-B2 Light-emitting element TORAY INDUSTRIES, INC. (JP) 2013-08-06 US disclosed
US-8502201-B2 Light-emitting element TORAY INDUSTRIES, INC. (JP) 2013-08-06 US disclosed
US-20120138907-A1 LIGHT-EMITTING DEVICE MATERIAL AND LIGHT-EMITTING DEVICE TORAY INDUSTRIES, INC. (JP) 2012-06-07 US disclosed
US-20120138907-A1 LIGHT-EMITTING DEVICE MATERIAL AND LIGHT-EMITTING DEVICE TORAY INDUSTRIES, INC. (JP) 2012-06-07 US disclosed
US-8084146-B2 Light-emitting device material and light-emitting device TORAY INDUSTRIES, INC. (JP) 2011-12-27 US disclosed
US-8084146-B2 Light-emitting device material and light-emitting device TORAY INDUSTRIES, INC. (JP) 2011-12-27 US disclosed
US-20110121268-A1 LIGHT-EMITTING ELEMENT TORAY INDUSTRIES, INC. (JP) 2011-05-26 US disclosed
US-20110121268-A1 LIGHT-EMITTING ELEMENT TORAY INDUSTRIES, INC. (JP) 2011-05-26 US disclosed
US-7901794-B2 Material for light-emitting element and light emitting element TORAY INDUSTRIES, INC. (JP) 2011-03-08 US disclosed
US-7901794-B2 Material for light-emitting element and light emitting element TORAY INDUSTRIES, INC. (JP) 2011-03-08 US disclosed
US-20090066245-A1 MATERIAL FOR LIGHT-EMITTING ELEMENT AND LIGHT EMITTING ELEMENT TORAY INDUSTRIES, INC. (JP) 2009-03-12 US disclosed
US-20090066245-A1 MATERIAL FOR LIGHT-EMITTING ELEMENT AND LIGHT EMITTING ELEMENT TORAY INDUSTRIES, INC. (JP) 2009-03-12 US disclosed
US-20070247063-A1 Light-Emitting Device Material and Light-Emitting Device TORAY INDUSTRIES INC. (JP) 2007-10-25 US disclosed
US-20070247063-A1 Light-Emitting Device Material and Light-Emitting Device TORAY INDUSTRIES INC. (JP) 2007-10-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120138907-A1 LIGHT-EMITTING DEVICE MATERIAL AND LIGHT-EMITTING DEVICE CRY1, MMS19, CRY2 L3MBTL1 167/4885KDM4E 3391/4885ATM 600/4885
US-20070247063-A1 Light-Emitting Device Material and Light-Emitting Device CRY1, CRY2, ATXN10 L3MBTL1 530/4885KDM4E 3893/4885ATM 1395/4885
US-20090066245-A1 MATERIAL FOR LIGHT-EMITTING ELEMENT AND LIGHT EMITTING ELEMENT PYM1, CRY1, S100A10 L3MBTL1 195/4885KDM4E 1639/4885ATM 2775/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.