Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | PKM | P14618 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HTR6 | P50406 | 2/20 | 0.35 |
| ▸ | CDK2 | P24941 | 4/20 | 0.35 |
| ▸ | COMT | P21964 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9890971 | 0.90 | HPGDS (0.38) | ALDH1A1KDM4EPKMSMN1; SMN2HTR6 | |
| SCHEMBL7909713 | 0.88 | HTR6 (0.37) | ALDH1A1KDM4EPKMHTR6CDK2 | |
| SCHEMBL7906965 | 0.79 | KDM4E (0.39) | ALDH1A1KDM4EPKMSMN1; SMN2HTR6 | |
| SCHEMBL15428933 | 0.78 | COMT (0.38) | ALDH1A1KDM4EPKMSMN1; SMN2HTR6 | |
| SCHEMBL9890972 | 0.78 | HTR6 (0.35) | ALDH1A1KDM4EPKMSMN1; SMN2HTR6 | |
| SCHEMBL15428932 | 0.77 | ADORA2A (0.36) | ALDH1A1KDM4EPKMCOMTUSP2 | |
| SCHEMBL9890976 | 0.77 | MAPT (0.35) | ALDH1A1KDM4EPKMSMN1; SMN2HTR6 | |
| SCHEMBL15428930 | 0.77 | COMT (0.34) | ALDH1A1KDM4EPKMSMN1; SMN2HTR6 | |
| SCHEMBL9890975 | 0.76 | ALDH1A1 (0.43) | ALDH1A1KDM4EPKMSMN1; SMN2COMT | |
| SCHEMBL15428931 | 0.76 | NPY5R (0.38) | ALDH1A1KDM4EPKMSMN1; SMN2COMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120142929-A1 | PROCESS FOR PREPARING SULFONYL QUINOLINES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142929-A1 | PROCESS FOR PREPARING SULFONYL QUINOLINES | GYS2, CYP3A7, GBA1 | ALDH1A1 771/4885KDM4E 2420/4885PKM 1120/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.