SCHEMBL9892443

SCHEMBL9892443

CCOC(=O)CN(/C=C/C=C1C(=O)CC(C)(C)CC1=O)CC(=O)OCC

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.40
ALDH1A1 P00352 7/20 0.37
KDM4E B2RXH2 4/20 0.37
TSHR P16473 3/20 0.37
HPGD P15428 1/20 0.37
ALOX15 P16050 1/20 0.35
MAPT P10636 6/20 0.35
USP2 O75604 1/20 0.35
PLA2G1B P04054 1/20 0.35
ATG4B Q9Y4P1 1/20 0.35
RAB9A P51151 2/20 0.34
POLB P06746 2/20 0.33
RECQL P46063 2/20 0.33
MAPK1 P28482 1/20 0.33
LMNA P02545 1/20 0.33
KMT2A Q03164 3/20 0.33
MEN1 O00255 2/20 0.33
NPSR1 Q6W5P4 1/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
HIF1A Q16665 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9889234 0.82 APP (0.41) APPALDH1A1KDM4EMAPTPOLB
SCHEMBL9892446 0.80 APP (0.39) APPALDH1A1TSHRALOX15MAPT
SCHEMBL12758233 0.76 APP (0.43) APPALDH1A1KDM4EMAPTPOLB
SCHEMBL9892476 0.75 APP (0.37) APPALDH1A1TSHRMAPTL3MBTL1
SCHEMBL9892452 0.75 KMT2A (0.41) APPALDH1A1ALOX15MAPTUSP2
SCHEMBL4544722 0.73 APP (0.41) APPALDH1A1KDM4EHPGDMAPT
SCHEMBL12310447 0.71 APP (0.41) APPALDH1A1HPGDMAPTPOLB
SCHEMBL12260820 0.71 APP (0.41) APPALDH1A1MAPTPOLBL3MBTL1
SCHEMBL13855924 0.70 POLB (0.61) APPALDH1A1KDM4EHPGDMAPT
SCHEMBL10098421 0.70 POLB (0.61) APPALDH1A1KDM4EHPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8652364-B2 Polymer film, ultraviolet absorber, merocyanine compound and process for preparing merocyanine compound FUJIFILM CORPORATION (JP) 2014-02-18 US disclosed
US-20120140161-A1 POLYMER FILM, RETARDATION FILM, POLARIZING PLATE, LIQUID CRYSTAL DISPLAY DEVICE AND ULTRAVIOLET ABSORBER FUJIFILM CORPORATION (JP) 2012-06-07 US disclosed
US-20110220843-A1 POLYMER FILM, ULTRAVIOLET ABSORBER, MEROCYANINE COMPOUND AND PROCESS FOR PREPARING MEROCYANINE COMPOUND FUJIFILM CORPORATION (JP) 2011-09-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110220843-A1 POLYMER FILM, ULTRAVIOLET ABSORBER, MEROCYANINE COMPOUND AND PROCESS FOR PREPARING MEROCYANINE COMPOUND HAMP, CRY1, CRY2 APP 97/4885ALDH1A1 1899/4885KDM4E 790/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.