SCHEMBL9892456

SCHEMBL9892456

CC(C)(C)C(=O)/C(C#N)=C/C=C/N(CC#N)CC#N

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.38
ALDH1A1 P00352 1/20 0.38
KMT2A Q03164 1/20 0.38
MAPT P10636 1/20 0.35
DPP4 P27487 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9889206 0.83 MEN1 (0.37) MEN1ALDH1A1KMT2AMAPT
SCHEMBL9892465 0.82 MCL1 (0.33) ALDH1A1
SCHEMBL9889307 0.81 MEN1 (0.35) MEN1ALDH1A1KMT2AMAPT
SCHEMBL9892451 0.77 CYP2C9 (0.38) MEN1ALDH1A1KMT2AMAPT
SCHEMBL9892464 0.75 DNM1 (0.38) MEN1ALDH1A1KMT2AMAPT
SCHEMBL12051138 0.75 DNM1 (0.38) MEN1ALDH1A1KMT2AMAPT
SCHEMBL13386046 0.70 EGFR (0.35) MEN1ALDH1A1KMT2AMAPT
SCHEMBL13386049 0.70 EGFR (0.35) MEN1ALDH1A1KMT2AMAPT
SCHEMBL9892457 0.70 APP (0.32)
SCHEMBL16328969 0.70 ZDHHC20 (0.40) MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220049068-A1 RESIN COMPOSITION, LIQUID COMPOSITION, COLORING AGENT COMPOUND, AND OPTICAL MATERIAL FUJIFILM CORPORATION (JP) 2022-02-17 US disclosed
US-10808130-B2 Protective sheet, image display device, spectacle lens, and spectacles FUJIFILM CORPORATION (JP) 2020-10-20 US disclosed
EP-3438712-A1 PROTECTION SHEET, IMAGE DISPLAY DEVICE, EYEGLASS LENS AND EYEGLASSES Fujifilm Corporation (JP) 2019-02-06 EP disclosed
US-8652364-B2 Polymer film, ultraviolet absorber, merocyanine compound and process for preparing merocyanine compound FUJIFILM CORPORATION (JP) 2014-02-18 US disclosed
US-20120140161-A1 POLYMER FILM, RETARDATION FILM, POLARIZING PLATE, LIQUID CRYSTAL DISPLAY DEVICE AND ULTRAVIOLET ABSORBER FUJIFILM CORPORATION (JP) 2012-06-07 US disclosed
US-20110220843-A1 POLYMER FILM, ULTRAVIOLET ABSORBER, MEROCYANINE COMPOUND AND PROCESS FOR PREPARING MEROCYANINE COMPOUND FUJIFILM CORPORATION (JP) 2011-09-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110220843-A1 POLYMER FILM, ULTRAVIOLET ABSORBER, MEROCYANINE COMPOUND AND PROCESS FOR PREPARING MEROCYANINE COMPOUND HAMP, CRY1, CRY2 MEN1 48/4885ALDH1A1 1899/4885KMT2A 1571/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.