SCHEMBL9892463

SCHEMBL9892463

CCS(=O)(=O)CC[Si](C)(C)C

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6723728 0.88 APEX1 (0.30)
SCHEMBL13924149 0.83
SCHEMBL16868758 0.79 CA2 (0.40) LMNA
SCHEMBL18133304 0.78
SCHEMBL17461607 0.78 CA2 (0.48)
SCHEMBL8695940 0.76 LMNA (0.36) LMNA
SCHEMBL12867622 0.75
SCHEMBL17921847 0.74 GCLC (0.30)
SCHEMBL9988374 0.74
SCHEMBL8339214 0.73 LMNA (0.40) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2490701-B9 CARDIOMYOCYTE PRODUCTION CELLULAR DYNAMICS INT INC (US) 2017-11-15 EP disclosed
US-9763782-B2 Apparatus for treating a heart valve EDWARDS LIFESCIENCES AG (CH) 2017-09-19 US disclosed
US-9684120-B2 Optical article having viscoelastic layer 3M INNOVATIVE PROPERTIES COMPANY (US) 2017-06-20 US disclosed
US-20170141290-A1 PIEZOELECTRIC ACTUATOR, STACKED ACTUATOR, PIEZOELECTRIC MOTOR, ROBOT, HAND, AND LIQUID TRANSPORT PUMP SEIKO EPSON CORPORATION (JP) 2017-05-18 US disclosed
US-20170079556-A1 NITRIC OXIDE CONCENTRATION TESTING DEVICE, NITRIC OXIDE CONCENTRATION TESTING SYSTEM, NITRIC OXIDE CONCENTRATION TESTING SERVER, AND NITRIC OXIDE CONCENTRATION TESTING TERMINAL DEVICE SEIKO EPSON CORPORATION (JP) 2017-03-23 US disclosed
US-20160354483-A1 COMPOUNDS, CONJUGATES AND COMPOSITIONS OF EPIPOLYTHIODIKETOPIPERAZINES AND POLYTHIODIKETOPIPERAZINES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2016-12-08 US disclosed
US-9512437-B2 Genetic mutations that disrupt dhurrin production in sorghum PURDUE RESEARCH FOUNDATION (US) 2016-12-06 US disclosed
US-9514655-B1 Mobile computing weight, diet, nutrition, and exercise management system with enhanced feedback and goal achieving functionality Nusbaum, Mark E. (US) 2016-12-06 US disclosed
US-20160351072-A1 Mobile Computing Weight, Diet, Nutrition, and Exercise Management System With Enhanced Feedback and Goal Achieving Functionality SMARTEN LLC 2016-12-01 US disclosed
US-9498845-B2 Pulse train annealing method and apparatus APPLIED MATERIALS, INC. (US) 2016-11-22 US disclosed
US-20110305629-A1 Anti-Alpha v Beta 6 Antibodies and Uses Thereof BIOGEN IDEC MA INC. (US) 2011-12-15 US disclosed
WO-2011153144-A1 ISOBUTANOL PRODUCTION USING YEASTS WITH MODIFIED TRANSPORTER EXPRESSION GEVO, INC. (US) 2011-12-08 WO disclosed
US-20110076096-A1 SYSTEM, METHOD AND APPARATUS FOR TOLERANCE RING CONTROL OF SLIP INTERFACE SLIDING FORCES SAINT-GOBAIN PERFORMANCE PLASTICS RENCOL LIMITED (GB) 2011-03-31 US disclosed
US-20100181195-A1 MICROFLUIDIC CHIP FOR AND A METHOD OF HANDLING FLUIDIC DROPLETS NXP B.V. (NL) 2010-07-22 US disclosed
US-20090137118-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE RENESAS TECHNOLOGY CORP. 2009-05-28 US disclosed
US-7526164-B2 Reflective polarizers containing polymer fibers 3M INNOVATIVE PROPERTIES COMPANY (US) 2009-04-28 US disclosed
US-20090085121-A1 Condensed Memory Cell Structure Using a FinFET SAMSUNG ELECTRONICS CO., LTD. (KR) 2009-04-02 US disclosed
US-20080181949-A1 Nanoemulsion Vaccines THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2008-07-31 US disclosed
US-20080165419-A1 REFLECTIVE POLARIZERS CONTAINING POLYMER FIBERS 3M INNOVATIVE PROPERTIES COMPANY 2008-07-10 US disclosed
US-20070154999-A1 SUCCINIC ACID - PRODUCING BACTERIUM AND PROCESS FOR PRODUCING SUCCINIC ACID AJINOMOTO CO., INC., (JP) 2007-07-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110305629-A1 Anti-Alpha v Beta 6 Antibodies and Uses Thereof ITGAV, ITGA6, ITGB6 LMNA 2915/4885
US-20160354483-A1 COMPOUNDS, CONJUGATES AND COMPOSITIONS OF EPIPOLYTHIODIKETOPIPERAZINES AND POLYTHIODIKETOPIPERAZINES DNPEP, NPEPPS, PIN1 LMNA 3893/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.