SCHEMBL9892676

SCHEMBL9892676

Cc1cccc2c3ccccc3n3ccnc3c12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FLT1 P17948 1/20 0.41
CDK8 P49336 1/20 0.41
CDK9 P50750 1/20 0.41
LIMK1 P53667 1/20 0.41
ROCK1 Q13464 1/20 0.41
CLK4 Q9HAZ1 1/20 0.41
ALKBH5 Q6P6C2 1/20 0.40
FTO Q9C0B1 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.39
HTR3E A5X5Y0 1/20 0.38
HTR3B O95264 1/20 0.38
HTR3A P46098 1/20 0.38
HTR3D Q70Z44 1/20 0.38
HTR3C Q8WXA8 1/20 0.38
MAPT P10636 4/20 0.36
ALDH1A1 P00352 1/20 0.36
AGER Q15109 1/20 0.36
KDM4E B2RXH2 2/20 0.36
MAPK8 P45983 5/20 0.35
CYP1A2 P05177 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25706382 0.89 FLT1 (0.39) FLT1CDK8CDK9LIMK1ROCK1
SCHEMBL29994225 0.88 FLT1 (0.41) FLT1CDK8CDK9LIMK1ROCK1
SCHEMBL17557193 0.88 FLT1 (0.41) FLT1CDK8CDK9LIMK1ROCK1
SCHEMBL21917534 0.83 PDE2A (0.40) FLT1CDK8CDK9LIMK1ROCK1
SCHEMBL20367893 0.81 MAPK8 (0.35) CDK8ROCK1HTR3EHTR3BHTR3A
SCHEMBL21298120 0.80 MAPK8 (0.38) CDK8ROCK1SMN1; SMN2HTR3EHTR3B
SCHEMBL840406 0.78 MAPK8 (0.41) CDK8ROCK1SMN1; SMN2HTR3EHTR3B
SCHEMBL29636632 0.78 MAPK8 (0.41) CDK8ROCK1SMN1; SMN2HTR3EHTR3B
SCHEMBL19606124 0.77 HTR3E (0.41) FLT1CDK8CDK9LIMK1ROCK1
SCHEMBL840252 0.76 MAPK8 (0.40) CDK8ROCK1SMN1; SMN2HTR3EHTR3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240224783-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-07-04 US disclosed
US-20230382935-A1 COMPOUND CONTAINING 1,3-DIKETONE LIGAND AND APPLICATION THEREOF, AND ORGANIC ELECTROLUMINESCENT DEVICE BEIJING GREEN GUARDEE TECHNOLOGY CO., LTD. (CN) 2023-11-30 US disclosed
US-11832456-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-11-28 US disclosed
US-20230371358-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-16 US disclosed
US-11780865-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-10-10 US disclosed
US-20230287011-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-14 US disclosed
US-11737349-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-08-22 US disclosed
US-11647667-B2 Organic electroluminescent compounds and organic light emitting devices using the same UNIVERSAL DISPLAY CORPORATION (US) 2023-05-09 US disclosed
US-11201298-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-12-14 US disclosed
EP-3750897-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2020-12-16 EP disclosed
EP-3424935-A1 PYRIDYL CARBENE PHOSPHORESCENT EMITTERS Universal Display Corporation (US) 2019-01-09 EP disclosed
US-20180198079-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2018-07-12 US disclosed
US-20180198079-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2018-07-12 US disclosed
US-9905767-B2 High-molecular compound and light-emitting element using same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-02-27 US disclosed
US-20150207077-A1 HIGH-MOLECULAR COMPOUND AND LIGHT-EMITTING ELEMENT USING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-07-23 US disclosed
US-20120138906-A1 CAPTURE AGENTS FOR UNSATURATED METAL COMPLEXES The University of Southern California USC Stevens Institute for Innovation (US) 2012-06-07 US disclosed
US-20110101856-A1 Ion-Pairing Soft Salts Based On Organometallic Complexes And Their Applications In Organic Light Emitting Diodes THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2011-05-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11832456-B2 Organic electroluminescent materials and devices CPNE4, CYBA, EPCAM FLT1 4097/4885CDK8 664/4885CDK9 897/4885
US-20180198079-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OSBP FLT1 4374/4885CDK8 2749/4885CDK9 1282/4885
US-11201298-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, OSBP FLT1 4374/4885CDK8 2749/4885CDK9 1282/4885
US-11647667-B2 Organic electroluminescent compounds and organic light emitting devices using the same OCIAD1, OCIAD2, ODC1 FLT1 3884/4885CDK8 3422/4885CDK9 2546/4885
US-20230287011-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OXGR1, OCIAD1 FLT1 2747/4885CDK8 3444/4885CDK9 2759/4885
US-11737349-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, OTC FLT1 4509/4885CDK8 3524/4885CDK9 2499/4885
US-20240224783-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ICOSLG FLT1 3665/4885CDK8 2550/4885CDK9 1635/4885
US-20150207077-A1 HIGH-MOLECULAR COMPOUND AND LIGHT-EMITTING ELEMENT USING SAME ARL1, GRK1, GNA11 FLT1 1617/4885CDK8 2096/4885CDK9 957/4885
US-11780865-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, OSBP FLT1 4274/4885CDK8 2688/4885CDK9 1345/4885
US-20230382935-A1 COMPOUND CONTAINING 1,3-DIKETONE LIGAND AND APPLICATION THEREOF, AND ORGANIC ELECTROLUMINESCENT DEVICE TLK1, TLK2, PDK3 FLT1 1207/4885CDK8 814/4885CDK9 537/4885
US-20110101856-A1 Ion-Pairing Soft Salts Based On Organometallic Complexes And Their Applications In Organic Light Emitting Diodes OCIAD2, ICOSLG, OCIAD1 FLT1 3782/4885CDK8 3254/4885CDK9 2439/4885
US-20230371358-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LIFR, SOD1, ROS1 FLT1 1961/4885CDK8 3127/4885CDK9 2074/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.