SCHEMBL9893626

SCHEMBL9893626

CCCCCCCCCCCCCCCCCCCCCCC(CC)N(C)C

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.41
DNM1 Q05193 5/20 0.40
TSHR P16473 1/20 0.40
THRB P10828 1/20 0.40
PLA2G1B P04054 1/20 0.39
PLA2G2A P14555 1/20 0.39
OPRM1 P35372 1/20 0.39
GPR84 Q9NQS5 2/20 0.37
FDPS P14324 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL37787 1.00 LMNA (0.41) LMNADNM1TSHRTHRBPLA2G1B
SCHEMBL29209175 1.00 LMNA (0.41) LMNADNM1TSHRTHRBPLA2G1B
SCHEMBL28664577 1.00 LMNA (0.41) LMNADNM1TSHRTHRBPLA2G1B
SCHEMBL22986852 1.00 LMNA (0.41) LMNADNM1TSHRTHRBPLA2G1B
SCHEMBL4798727 1.00 LMNA (0.41) LMNADNM1TSHRTHRBPLA2G1B
SCHEMBL24990076 1.00 LMNA (0.41) LMNADNM1TSHRTHRBPLA2G1B
SCHEMBL4797069 1.00 LMNA (0.41) LMNADNM1TSHRTHRBPLA2G1B
SCHEMBL37601 1.00 LMNA (0.41) LMNADNM1TSHRTHRBPLA2G1B
SCHEMBL14840061 1.00 LMNA (0.41) LMNADNM1TSHRTHRBPLA2G1B
SCHEMBL14840100 1.00 LMNA (0.41) LMNADNM1TSHRTHRBPLA2G1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170000723-A1 ORGANOPOLYSILOXANE AND HAIR COSMETIC AND METHOD FOR PRODUCING THEREOF SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-01-05 US disclosed
US-8927751-B2 Hair care cosmetic SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-01-06 US disclosed
US-20120149930-A1 HAIR CARE COSMETIC SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-06-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170000723-A1 ORGANOPOLYSILOXANE AND HAIR COSMETIC AND METHOD FOR PRODUCING THEREOF NR5A2, H1-5, H1-2 LMNA 4470/4885DNM1 4636/4885TSHR 421/4885
US-20120149930-A1 HAIR CARE COSMETIC COL1A1, POLR1C, COL2A1 LMNA 872/4885DNM1 4662/4885TSHR 1896/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.