Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3802499 | 0.94 | HSD11B1 (0.33) | HSD11B1 | |
| SCHEMBL987090 | 0.79 | — | — | |
| SCHEMBL7006923 | 0.79 | — | — | |
| SCHEMBL35517 | 0.79 | — | — | |
| SCHEMBL9203723 | 0.79 | — | — | |
| SCHEMBL10893172 | 0.79 | — | — | |
| SCHEMBL10392521 | 0.79 | — | — | |
| SCHEMBL11247907 | 0.77 | — | — | |
| SCHEMBL9577684 | 0.74 | KMT2A (0.32) | — | |
| SCHEMBL9564651 | 0.72 | TTR (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200085856-A1 | ION BINDING POLYMERS AND USES THEREOF | ILYPSA, INC. | 2020-03-19 | — | — | US | disclosed |
| EP-3574896-A1 | ION BINDING POLYMERS AND USES THEREOF | Relypsa, Inc. (US) | 2019-12-04 | — | — | EP | disclosed |
| US-10485821-B2 | Ion binding polymers and uses thereof | VIFOR (INTERNATIONAL) LTD. (CH) | 2019-11-26 | — | — | US | disclosed |
| EP-3219312-B1 | ION BINDING POLYMERS AND USES THEREOF | RELYPSA INC (US) | 2019-01-30 | — | — | EP | disclosed |
| EP-3219312-A1 | ION BINDING POLYMERS AND USES THEREOF | Relypsa, Inc. (US) | 2017-09-20 | — | — | EP | disclosed |
| US-20160317572-A1 | ION BINDING POLYMERS AND USES THEREOF | VIFOR (INTERNATIONAL) LTD. (CH) | 2016-11-03 | — | — | US | disclosed |
| US-20160082039-A1 | ION BINDING POLYMERS AND USES THEREOF | RELYPSA, INC. | 2016-03-24 | — | — | US | disclosed |
| US-8889115-B2 | Ion binding polymers and uses thereof | RELYPSA, INC. (US) | 2014-11-18 | — | — | US | disclosed |
| US-20140286891-A1 | ION BINDING POLYMERS AND USES THEREOF | ILYPSA, INC. | 2014-09-25 | — | — | US | disclosed |
| US-8778324-B2 | Ion binding polymers and uses thereof | RELYPSA, INC. (US) | 2014-07-15 | — | — | US | disclosed |
| US-7488495-B2 | Ion binding polymers and uses thereof | RELYPSA, INC. (US) | 2009-02-10 | — | — | US | disclosed |
| US-20080241093-A1 | A potassium-binding polymer of a crosslinked ion exchange polymer having acid groups and an alpha/beta electronegative group in a bead form as an oral dosage; renal insufficiency; congestive heart failure; hyperkalemia; high preferential binding capaciity; stability; nonabsorbent; nontoxic | RELYPSA, INC. (US) | 2008-10-02 | — | — | US | disclosed |
| US-20080241092-A1 | Administering a potassium-binding polymer of a crosslinked ion exchange polymer having acid groups and an alpha/beta electronegative group in a bead form as an oral dosage; renal insufficiency; congestive heart failure; hyperkalemia; high preferential binding capaciity; stability; nonabsorbent; nontoxic | RELYPSA, INC. (US) | 2008-10-02 | — | — | US | disclosed |
| US-20080233073-A1 | Administering potassium binding polymer of alpha-fluoroacrylic acid comprising counterion of calcium crosslinked with divinylbenzene, (m)ethylenebisacrylamide, N,N'-bis(vinylsulfonylacetyl) ethylene diamine, 1,3-bis(vinylsulfonyl) 2-propanol, vinylsulfone, polyvinyl ether, polyallylether; hyperkalemia | RELYPSA, INC. (US) | 2008-09-25 | — | — | US | disclosed |
| EP-1732523-A4 | ION BINDING POLYMERS AND USES THEREOF | ILYPSA INC (US) | 2007-06-06 | — | — | EP | disclosed |
| EP-1732523-A1 | ION BINDING POLYMERS AND USES THEREOF | Ilypsa, Inc. (US) | 2006-12-20 | — | — | EP | disclosed |
| WO-2005097081-A1 | ION BINDING POLYMERS AND USES THEREOF | ILYPSA, INC. (US) | 2005-10-20 | — | — | WO | disclosed |
| US-20050220752-A1 | Ion binding polymers and uses thereof | VIFOR (INTERNATIONAL) LTD. (CH) | 2005-10-06 | — | — | US | disclosed |
| US-20050220751-A1 | Ion binding polymers and uses thereof | VIFOR (INTERNATIONAL) LTD. (CH) | 2005-10-06 | — | — | US | disclosed |
| US-4169936-A | CROWN ETHER AND N-ACYL PYRROLIDONE ACTIVATED COPOLYMERIZATION OF 2-PYRROLIDONE AND CAPROLACTAM | CHEVRON RESEARCH COMPANY (US) | 1979-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200085856-A1 | ION BINDING POLYMERS AND USES THEREOF | ATP6V1B1, KCNN3, SLC9A3 | HSD11B1 2364/4885 |
| US-20160082039-A1 | ION BINDING POLYMERS AND USES THEREOF | ATP6V1B1, KCNN3, SLC9A3 | HSD11B1 2364/4885 |
| US-20080233073-A1 | Administering potassium binding polymer of alpha-fluoroacrylic acid comprising counterion of calcium crosslinked with divinylbenzene, (m)ethylenebisacrylamide, N,N'-bis(vinylsulfonylacetyl) ethylene diamine, 1,3-bis(vinylsulfonyl) 2-propanol, vinylsulfone, polyvinyl ether, polyallylether; hyperkalemia | KCNH3, KCNAB1, KCNMB1 | HSD11B1 1689/4885 |
| US-20080241092-A1 | Administering a potassium-binding polymer of a crosslinked ion exchange polymer having acid groups and an alpha/beta electronegative group in a bead form as an oral dosage; renal insufficiency; congestive heart failure; hyperkalemia; high preferential binding capaciity; stability; nonabsorbent; nontoxic | KCNN3, ATP6V1B1, KCNK3 | HSD11B1 2628/4885 |
| US-20140286891-A1 | ION BINDING POLYMERS AND USES THEREOF | ATP6V1B1, KCNN3, SLC9A3 | HSD11B1 2364/4885 |
| US-10485821-B2 | Ion binding polymers and uses thereof | ATP6V1B1, KCNN3, SLC9A3 | HSD11B1 2364/4885 |
| US-20160317572-A1 | ION BINDING POLYMERS AND USES THEREOF | ATP6V1B1, KCNN3, SLC9A3 | HSD11B1 2364/4885 |
| US-20080241093-A1 | A potassium-binding polymer of a crosslinked ion exchange polymer having acid groups and an alpha/beta electronegative group in a bead form as an oral dosage; renal insufficiency; congestive heart failure; hyperkalemia; high preferential binding capaciity; stability; nonabsorbent; nontoxic | KCNN3, KCNK3, KCNK9 | HSD11B1 2399/4885 |
| US-20050220752-A1 | Ion binding polymers and uses thereof | ATP6V1B1, KCNN3, SLC9A3 | HSD11B1 2364/4885 |
| US-20050220751-A1 | Ion binding polymers and uses thereof | ATP6V1B1, KCNN3, SLC9A3 | HSD11B1 2364/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.