Sugi Predict

Sugi Predict / Compounds / SCHEMBL989408

SCHEMBL989408

SCHEMBL989408

COC(=O)c1cc2occc2[nH]1

nearest known ligand 0.65

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ DAO P14920 2/20 0.65
▸ GAA P10253 3/20 0.50
▸ POLB P06746 1/20 0.48
▸ CYP1A2 P05177 1/20 0.45
▸ CREBBP Q92793 1/20 0.44
▸ XDH P47989 3/20 0.43
▸ PSMB8 P28062 1/20 0.43
▸ ULK1 O75385 1/20 0.40
▸ GLA P06280 2/20 0.40
▸ KDM4E B2RXH2 1/20 0.40
▸ MAPK1 P28482 1/20 0.38
▸ MAPT P10636 2/20 0.37
▸ THRB P10828 1/20 0.36
▸ SMN1; SMN2 Q16637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12903488 0.87 DAO (0.61) DAOGAAPOLBCYP1A2CREBBP
SCHEMBL12864371 0.86 DAO (0.69) DAOGAAPOLBCREBBPPSMB8
SCHEMBL12864370 0.84 DAO (0.61) DAOGAAPOLBCREBBPPSMB8
SCHEMBL12864196 0.83 DAO (0.65) DAOGAAPOLBCREBBPXDH
SCHEMBL12864289 0.83 DAO (0.52) DAOGAAPOLBCYP1A2CREBBP
SCHEMBL12864292 0.83 DAO (0.52) DAOGAAPOLBCREBBPXDH
SCHEMBL1171015 0.83 DAO (0.59) DAOGAAPOLBGLAKDM4E
SCHEMBL12864273 0.83 DAO (0.59) DAOGAAPOLBCYP1A2CREBBP
SCHEMBL12880134 0.83 DAO (0.59) DAOGAAPOLBCREBBPPSMB8
SCHEMBL1171401 0.83 DAO (0.59) DAOGAAPOLBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4626860-A1 FUSED PYRROLYL-SULFONAMIDE COMPOUNDS ReWind Therapeutics NV (BE) 2025-10-08 — — EP disclosed
WO-2024115733-A1 FUSED PYRROLYL-SULFONAMIDE COMPOUNDS REWIND THERAPEUTICS NV (BE) 2024-06-06 — — WO disclosed
US-20240175141-A1 BIOBASED AND BIODEGRADABLE CORROSION INHIBITION COMPOSITION ZestBio, Inc. 2024-05-30 — — US disclosed
WO-2024081967-A2 BIOBASED AND BIODEGRADABLE CORROSION INHIBITION COMPOSITION ZestBio, Inc. (US) 2024-04-18 — — WO disclosed
EP-3313846-B1 THIENOPYRROLE COMPOUNDS AND USES THEREOF AS INHIBITORS OF OPLOPHORUS-DERIVED LUCIFERASES PROMEGA CORP (US) 2020-05-06 — — EP disclosed
US-20200063110-A1 THIENOPYRROLE COMPOUNDS AND USES THEREOF PROMEGA CORPORATION 2020-02-27 — — US disclosed
US-10253035-B2 Eis inhibitors UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 2019-04-09 — — US disclosed
US-20180162867-A1 EIS INHIBITORS UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION 2018-06-14 — — US disclosed
EP-3313846-A1 THIENOPYRROLE COMPOUNDS AND USES THEREOF AS INHIBITORS OF OPLOPHORUS-DERIVED LUCIFERASES Promega Corporation (US) 2018-05-02 — — EP disclosed
US-20160376568-A1 THIENOPYRROLE COMPOUNDS AND USES THEREOF JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT 2016-12-29 — — US disclosed
US-20080058395-A1 Fused heterocyclic inhibitors of D-amino acid oxidase SEPRACOR INC. (US) 2008-03-06 — — US disclosed
US-20080058395-A1 Fused heterocyclic inhibitors of D-amino acid oxidase SEPRACOR INC. (US) 2008-03-06 — — US disclosed
US-20080058395-A1 Fused heterocyclic inhibitors of D-amino acid oxidase SEPRACOR INC. (US) 2008-03-06 — — US disclosed
WO-2008005456-A2 FUSED HETEROCYCLIC INHIBITORS OF D-AMINO ACID OXIDASE SEPRACOR INC. (US) 2008-01-10 — — WO disclosed
US-20080004327-A1 FLUORO-SUBSTITUTED INHIBITORS OF D-AMINO ACID OXIDASE SEPRACOR INC. (US) 2008-01-03 — — US disclosed
US-20080004327-A1 FLUORO-SUBSTITUTED INHIBITORS OF D-AMINO ACID OXIDASE SEPRACOR INC. (US) 2008-01-03 — — US disclosed
US-20080004327-A1 FLUORO-SUBSTITUTED INHIBITORS OF D-AMINO ACID OXIDASE SEPRACOR INC. (US) 2008-01-03 — — US disclosed
WO-2007068621-A1 NOVEL FUSED PYRROLE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2007-06-21 — — WO disclosed
US-20070142452-A1 Fused pyrrole derivatives HOFFMANN-LA ROCHE INC. 2007-06-21 — — US disclosed
US-6479527-B1 Bicyclic pyrrole derivatives as MCP-1 inhibitors ASTRAZENECA UK LIMITED (GB) 2002-11-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160376568-A1 THIENOPYRROLE COMPOUNDS AND USES THEREOF THOP1, TYMP, CREBBP DAO 1415/4885GAA 3964/4885POLB 2859/4885
US-20080058395-A1 Fused heterocyclic inhibitors of D-amino acid oxidase DAO, DDO, AOX1 DAO 1/4885GAA 1246/4885POLB 1235/4885
US-20070142452-A1 Fused pyrrole derivatives CMA1, PREP, CPA3 DAO 829/4885GAA 119/4885POLB 1631/4885
US-20180162867-A1 EIS INHIBITORS EP300, ACAT1, ACAT2 DAO 1488/4885GAA 274/4885POLB 1098/4885
US-10253035-B2 Eis inhibitors EP300, ACAT1, ACAT2 DAO 1488/4885GAA 274/4885POLB 1098/4885
US-20200063110-A1 THIENOPYRROLE COMPOUNDS AND USES THEREOF THOP1, TYMP, CREBBP DAO 1415/4885GAA 3964/4885POLB 2859/4885
US-20080004327-A1 FLUORO-SUBSTITUTED INHIBITORS OF D-AMINO ACID OXIDASE DAO, DDO, AOX1 DAO 1/4885GAA 830/4885POLB 1205/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.