Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.61 |
| ▸ | KAT6A | Q92794 | 5/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.52 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.48 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26282598 | 0.85 | RAPGEF3 (0.60) | KAT6AL3MBTL1RAPGEF3LARS1ALDH1A1 | |
| SCHEMBL30549044 | 0.85 | RAPGEF3 (0.60) | KAT6AL3MBTL1RAPGEF3LARS1ALDH1A1 | |
| SCHEMBL5394506 | 0.82 | CA1 (0.57) | LARS1ALDH1A1GAACA12CA1 | |
| SCHEMBL17943496 | 0.81 | L3MBTL1 (0.58) | KAT6AL3MBTL1RAPGEF3LARS1ALDH1A1 | |
| SCHEMBL18019205 | 0.81 | LARS1 (0.61) | ACACBKAT6ARAPGEF3LARS1 | |
| SCHEMBL19792928 | 0.80 | CA2 (0.53) | ACACBKAT6ARAPGEF3LARS1ALDH1A1 | |
| SCHEMBL7299158 | 0.80 | ACACB (0.60) | ACACBKAT6AL3MBTL1ALDH1A1LMNA | |
| SCHEMBL12550112 | 0.79 | BCL2 (0.54) | GAAMEN1KMT2ACA12CA1 | |
| SCHEMBL8889970 | 0.79 | ACACB (0.66) | ACACBKAT6AALDH1A1LMNAGAA | |
| SCHEMBL8901368 | 0.79 | ACACB (0.66) | ACACBKAT6AALDH1A1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120148604-A1 | TRP INHIBITORS AND USES THEREOF | TRANSPOSAGEN BIOPHARMACEUTICALS, INC. (US) | 2012-06-14 | — | — | US | disclosed |
| US-20120148604-A1 | TRP INHIBITORS AND USES THEREOF | TRANSPOSAGEN BIOPHARMACEUTICALS, INC. (US) | 2012-06-14 | — | — | US | disclosed |
| US-20120148604-A1 | TRP INHIBITORS AND USES THEREOF | TRANSPOSAGEN BIOPHARMACEUTICALS, INC. (US) | 2012-06-14 | — | — | US | disclosed |
| US-20080199807-A1 | OPTICAL INFORMATION RECORDING MEDIUM, METHOD OF RECORDING INFORMATION AND METHOD OF USING COMPOUND | FUJIFILM CORPORATION (JP) | 2008-08-21 | — | — | US | disclosed |
| US-20080199807-A1 | OPTICAL INFORMATION RECORDING MEDIUM, METHOD OF RECORDING INFORMATION AND METHOD OF USING COMPOUND | FUJIFILM CORPORATION (JP) | 2008-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120148604-A1 | TRP INHIBITORS AND USES THEREOF | TRPC4, TRPC1, TRPC3 | ACACB 3596/4885KAT6A 3055/4885L3MBTL1 413/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.