Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GABRP | O00591 | 1/20 | 0.32 |
| ▸ | GABRD | O14764 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3512075 | 0.89 | ALDH1A1 (0.39) | ALDH1A1MEN1CYP1A2CYP2C19KMT2A | |
| SCHEMBL11398940 | 0.76 | NPC1 (0.42) | ALDH1A1MEN1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL13140958 | 0.75 | ALDH1A1 (0.40) | ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL24027230 | 0.73 | ALDH1A1 (0.43) | ALDH1A1MEN1CYP1A2CYP2C19KMT2A | |
| SCHEMBL30155004 | 0.73 | ALDH1A1 (0.43) | ALDH1A1MEN1CYP1A2CYP2C19KMT2A | |
| Hydrochloric Acid SCHEMBL2938984 | 0.73 | ALDH1A1 (0.39) | ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL2933128 | 0.73 | ALDH1A1 (0.41) | ALDH1A1CYP1A2CYP2C19 | |
| Trifluoroacetic Acid SCHEMBL27817954 | 0.72 | NPC1 (0.54) | ALDH1A1CYP1A2KDM4E | |
| SCHEMBL14420953 | 0.72 | POLB (0.46) | ALDH1A1KMT2A | |
| SCHEMBL11397006 | 0.70 | THRB (0.37) | ALDH1A1MEN1KMT2AGABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120149718-A1 | Amido Compounds | BROTHERTON-PLEISS CHRISTINE E (US) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149718-A1 | Amido Compounds | P2RX7, P2RX3, P2RX2 | ALDH1A1 2230/4885DPP4 962/4885F2 2094/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.