Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1464656 | 0.78 | PTGS2 (0.49) | SCDPTGS2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9894832 | 0.71 | CSNK1D (0.70) | SCDPTGS2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1463901 | 0.69 | CNR2 (0.59) | SCDNPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL9897188 | 0.68 | PTPN2 (0.46) | SCDPTGS2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10005070 | 0.68 | KDM4E (0.49) | NPC1RAB9ASMN1; SMN2TP53MAPT | |
| SCHEMBL9897184 | 0.67 | PTGS2 (0.44) | SCDPTGS2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13490131 | 0.66 | MAPT (0.59) | SCDNPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL30606758 | 0.66 | XDH (0.45) | SCDNPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL1465673 | 0.66 | CNR2 (0.51) | SCDNPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL9895215 | 0.66 | NPC1 (0.44) | SCDPTGS2NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120149718-A1 | Amido Compounds | BROTHERTON-PLEISS CHRISTINE E (US) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149718-A1 | Amido Compounds | P2RX7, P2RX3, P2RX2 | SCD 3825/4885PTGS2 1485/4885NPC1 599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.