Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 6/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15013474 | 0.82 | DHODH (0.54) | DHODHLMNATSHRGAA | |
| SCHEMBL6652685 | 0.78 | KDM4E (0.49) | DHODHKDM4EALDH1A1HPGDLMNA | |
| SCHEMBL9899175 | 0.77 | SMN1; SMN2 (0.47) | DHODHKDM4EALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL28261476 | 0.76 | KDM4E (0.50) | DHODHKDM4EALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL14363733 | 0.75 | KCNA5 (0.50) | KDM4EALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL28261472 | 0.73 | KDM4E (0.50) | DHODHKDM4EALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL9896760 | 0.72 | PLA2G2A (0.53) | DHODHKDM4EALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL13499832 | 0.72 | KCNA5 (0.48) | KDM4EALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9639864 | 0.72 | GFER (0.52) | KDM4EALDH1A1CYP1A2CYP2C19HPGD | |
| SCHEMBL9934163 | 0.71 | BACE1 (0.45) | DHODHKDM4ELMNAHSD17B10BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9028728-B2 | Photochromic materials that include indeno-fused naphthopyrans | TRANSITIONS OPTICAL, INC. (US) | 2015-05-12 | — | — | US | disclosed |
| US-20120145973-A1 | Photochromic Materials That Include Indeno-Fused Naphthopyrans | TRANSITIONS OPTICAL INC. (US) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120145973-A1 | Photochromic Materials That Include Indeno-Fused Naphthopyrans | NQO1, INTS6, IPO4 | DHODH 352/4885KDM4E 1472/4885ALDH1A1 431/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.