Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TKT | P29401 | 1/20 | 0.32 |
| ▸ | ACACA | Q13085 | 1/20 | 0.32 |
| ▸ | ICMT | O60725 | 1/20 | 0.32 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL939319 | 0.86 | NAPRT (0.34) | ALDH1A1GAATKT | |
| SCHEMBL940930 | 0.82 | AKR1B1 (0.41) | CA2ALDH1A1 | |
| SCHEMBL9899603 | 0.81 | ICMT (0.36) | HTTSIRT1CA2ALDH1A1ATM | |
| SCHEMBL29202692 | 0.81 | LMNA (0.36) | HTTSIRT1CA2SMN1; SMN2ATM | |
| SCHEMBL18131334 | 0.81 | HTT (0.42) | HTTSIRT1CA2ALDH1A1TKT | |
| SCHEMBL838041 | 0.77 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2ACLYGAA | |
| SCHEMBL31582761 | 0.75 | ALDH1A1 (0.34) | ALDH1A1TKT | |
| SCHEMBL31583141 | 0.74 | EPHX1 (0.38) | HTTALDH1A1SMN1; SMN2GAATKT | |
| SCHEMBL7083846 | 0.73 | CD274 (0.41) | — | |
| SCHEMBL5745630 | 0.73 | CTRC (0.39) | SMN1; SMN2NPSR1TKT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012078608-A1 | PREPARATION OF PHANTASMIDINE AND ANALOGUES THEREOF | BRANDEIS UNIVERSITY (US) | 2012-06-14 | — | — | WO | disclosed |