Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | C1S | P09871 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TPMT | P51580 | 1/20 | 0.32 |
| ▸ | TSPO | P30536 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | SELL | P14151 | 1/20 | 0.30 |
| ▸ | SELP | P16109 | 1/20 | 0.30 |
| ▸ | SELE | P16581 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27335072 | 0.79 | ALDH1A1 (0.45) | ALDH1A1TSHRPRSS1PRSS2C1S | |
| SCHEMBL13746874 | 0.77 | ALDH1A1 (0.43) | ALDH1A1TSHRPRSS1PRSS2C1S | |
| SCHEMBL9482520 | 0.75 | ALDH1A1 (0.61) | ALDH1A1TSHRPRSS1PRSS2C1S | |
| SCHEMBL7046205 | 0.73 | ALDH1A1 (0.44) | ALDH1A1TSHRPRSS1PRSS2C1S | |
| SCHEMBL21787888 | 0.73 | ACHE (0.52) | ALDH1A1ACHESIGMAR1 | |
| Hydrazine SCHEMBL28654545 | 0.71 | ALDH1A1 (0.69) | ALDH1A1TSHRPRSS1PRSS2C1S | |
| Methylamine SCHEMBL28203537 | 0.71 | ALDH1A1 (0.69) | ALDH1A1TSHRPRSS1PRSS2C1S | |
| SCHEMBL8764966 | 0.71 | ALDH1A1 (0.42) | ALDH1A1TSHRPRSS1PRSS2C1S | |
| SCHEMBL43548 | 0.71 | ALDH1A1 (0.50) | ALDH1A1TSHRACHETPMTTSPO | |
| SCHEMBL13509012 | 0.71 | TSHR (0.42) | ALDH1A1TSHRPRSS1PRSS2C1S |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220006020-A1 | DI-, TRI- AND TETRAPHENYLINDANE DERIVATES AND THEIR USE IN ORGANIC ELECTRONICS | DOTTIKON ES HOLDING AG (CH) | 2022-01-06 | — | — | US | disclosed |
| EP-3650438-A1 | DI-, TRI- AND TETRAPHENYLINDANE DERIVATIVES AND THEIR USE IN ORGANIC ELECTRONICS | DOTTIKON ES HOLDING AG (CH) | 2020-05-13 | — | — | EP | disclosed |
| US-20200075862-A1 | INDANE DERIVATIVES AND THEIR USE IN ORGANIC ELECTRONICS | DOTTIKON ES HOLDING AG (CH) | 2020-03-05 | — | — | US | disclosed |
| EP-2649150-A2 | BIS(SULFONYL)BIARYL DERIVATIVES AS ELECTRON TRANSPORTING AND/OR HOST MATERIALS | Georgia Tech Research Corporation (US) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012078770-A2 | BIS(SULFONYL)BIARYL DERIVATIVES AS ELECTRON TRANSPORTING AND/OR HOST MATERIALS | GEORGIA TECH RESEARCH CORPORATION (US) | 2012-06-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220006020-A1 | DI-, TRI- AND TETRAPHENYLINDANE DERIVATES AND THEIR USE IN ORGANIC ELECTRONICS | NR0B2, KCNJ2, TRRAP | ALDH1A1 2569/4885TSHR 1794/4885PRSS1 4317/4885 |
| US-20200075862-A1 | INDANE DERIVATIVES AND THEIR USE IN ORGANIC ELECTRONICS | KCNJ2, KCNA2, CYP2J2 | ALDH1A1 1964/4885TSHR 4067/4885PRSS1 4157/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.