Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9905735 | 0.86 | KDM4E (0.48) | KMT2AKDM4EGAAP2RX7ALDH1A1 | |
| SCHEMBL9902516 | 0.75 | GAA (0.40) | KMT2AKDM4EGAAP2RX7SMN1; SMN2 | |
| SCHEMBL9903243 | 0.75 | KDM4E (0.58) | KMT2AKDM4EGAAHTTALDH1A1 | |
| SCHEMBL17271385 | 0.74 | KMT2A (0.40) | KMT2AKDM4EGAAP2RX4P2RX7 | |
| SCHEMBL9902885 | 0.74 | KMT2A (0.40) | KMT2AKDM4EGAAP2RX4P2RX7 | |
| SCHEMBL9902255 | 0.73 | KDM4E (0.50) | KMT2AKDM4EGAAALDH1A1 | |
| SCHEMBL9902954 | 0.71 | ALDH1A1 (0.41) | KMT2AKDM4EGAASMN1; SMN2RAB9A | |
| SCHEMBL9902470 | 0.70 | KDM4E (0.41) | KMT2AKDM4EGAAHTTALDH1A1 | |
| SCHEMBL9902803 | 0.70 | GAA (0.41) | KMT2AKDM4EGAASMN1; SMN2RAB9A | |
| SCHEMBL9902131 | 0.70 | KMT2A (0.35) | KMT2AKDM4EGAAP2RX4P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2649048-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | Radikal Therapeutics Inc. (US) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012077108-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | RADIKAL THERAPEUTICS INC. (US) | 2012-06-14 | — | — | WO | disclosed |