Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 3/20 | 0.32 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
| ▸ | CA9 | Q16790 | 3/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.32 |
| ▸ | APBA1 | Q02410 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9902283 | 0.92 | KDM4E (0.35) | KDM4EGAAKMT2AGRM5FFAR2 | |
| SCHEMBL9902713 | 0.86 | GRM5 (0.33) | KDM4EGAAKMT2AGRM5FFAR2 | |
| SCHEMBL16994520 | 0.80 | KDM4E (0.37) | KDM4EGAAKMT2AGRM5FFAR2 | |
| SCHEMBL9902556 | 0.78 | GAA (0.38) | KDM4EGAAKMT2AGRM5ALDH1A1 | |
| SCHEMBL9902803 | 0.76 | GAA (0.41) | KDM4EGAAKMT2ACA1CA2 | |
| SCHEMBL9905735 | 0.75 | KDM4E (0.48) | KDM4EGAAKMT2ACA1CA2 | |
| SCHEMBL16994486 | 0.74 | KDM4E (0.32) | KDM4EGAAKMT2AGRM5SLC6A2 | |
| SCHEMBL9903243 | 0.73 | KDM4E (0.58) | KDM4EGAAKMT2ACA1CA2 | |
| SCHEMBL9902476 | 0.72 | KDM4E (0.40) | KDM4EGAAKMT2ACA1CA2 | |
| SCHEMBL9902365 | 0.72 | KMT2A (0.39) | KDM4EGAAKMT2AGRM5HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2649048-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | Radikal Therapeutics Inc. (US) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012077108-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | RADIKAL THERAPEUTICS INC. (US) | 2012-06-14 | — | — | WO | disclosed |