Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.36 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | PRKACA | P17612 | 1/20 | 0.33 |
| ▸ | FRK | P42685 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | NEK4 | P51957 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9901787 | 0.84 | GAA (0.43) | KDM4EGAAKMT2AALDH1A1ALOX15 | |
| SCHEMBL9903261 | 0.83 | KDM4E (0.42) | KDM4EGAAKMT2ACA1CA2 | |
| SCHEMBL9902803 | 0.78 | GAA (0.41) | KDM4EGAAKMT2AALDH1A1CA1 | |
| SCHEMBL16994518 | 0.77 | KDM4E (0.51) | KDM4EGAAKMT2AALDH1A1ALOX15 | |
| SCHEMBL9902365 | 0.76 | KMT2A (0.39) | KDM4EGAAKMT2AALDH1A1CA1 | |
| SCHEMBL9903032 | 0.76 | RECQL (0.37) | KDM4EGAAKMT2AALDH1A1EPHX1 | |
| SCHEMBL9903173 | 0.75 | EPHX1 (0.47) | KDM4EALDH1A1EPHX1EPHX2MDM2 | |
| SCHEMBL9902043 | 0.75 | KDM4E (0.39) | KDM4EGAAKMT2A | |
| SCHEMBL9902251 | 0.75 | KMT2A (0.51) | KDM4EGAAKMT2AALDH1A1L3MBTL1 | |
| SCHEMBL9905735 | 0.75 | KDM4E (0.48) | KDM4EGAAKMT2AALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2649048-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | Radikal Therapeutics Inc. (US) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012077108-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | RADIKAL THERAPEUTICS INC. (US) | 2012-06-14 | — | — | WO | disclosed |