Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9902251 | 0.86 | KMT2A (0.51) | KDM4EGAAKMT2AALDH1A1P2RX7 | |
| SCHEMBL17271395 | 0.80 | KDM4E (0.43) | KDM4EGAAKMT2AGSK3AGSK3B | |
| SCHEMBL16994494 | 0.80 | KDM4E (0.43) | KDM4EGAAKMT2AGSK3AGSK3B | |
| SCHEMBL9902954 | 0.75 | ALDH1A1 (0.41) | KDM4EGAAKMT2AALDH1A1 | |
| SCHEMBL9902803 | 0.75 | GAA (0.41) | KDM4EGAAKMT2AALDH1A1CA1 | |
| SCHEMBL9902470 | 0.75 | KDM4E (0.41) | KDM4EGAAKMT2AALDH1A1CA1 | |
| SCHEMBL9903243 | 0.75 | KDM4E (0.58) | KDM4EGAAKMT2AGSK3AGSK3B | |
| SCHEMBL9902233 | 0.74 | KDM4E (0.38) | KDM4EGAAKMT2AGSK3AGSK3B | |
| SCHEMBL9902232 | 0.74 | KDM4E (0.38) | KDM4EGAAKMT2AGSK3AGSK3B | |
| SCHEMBL9905737 | 0.73 | KDM4E (0.47) | KDM4EGAAKMT2AALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2649048-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | Radikal Therapeutics Inc. (US) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012077108-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | RADIKAL THERAPEUTICS INC. (US) | 2012-06-14 | — | — | WO | disclosed |