Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | CA12 | O43570 | 3/20 | 0.49 |
| ▸ | CA9 | Q16790 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11039288 | 0.83 | CA12 (0.61) | POLBLMNAALDH1A1TDP1TSHR | |
| SCHEMBL11039286 | 0.83 | CA12 (0.61) | POLBLMNAALDH1A1TDP1TSHR | |
| SCHEMBL29790508 | 0.83 | NPC1 (0.69) | POLBLMNAALDH1A1MAPK1TDP1 | |
| SCHEMBL182738 | 0.81 | LMNA (0.67) | LMNAALDH1A1TDP1SMN1; SMN2HTT | |
| Water SCHEMBL28154432 | 0.79 | LMNA (0.64) | LMNAALDH1A1TDP1SMN1; SMN2HTT | |
| Hydrochloric Acid SCHEMBL19211700 | 0.79 | LMNA (0.64) | LMNAALDH1A1TDP1SMN1; SMN2HTT | |
| Hydrochloric Acid SCHEMBL1017218 | 0.79 | LMNA (0.64) | LMNAALDH1A1TDP1SMN1; SMN2HTT | |
| SCHEMBL23555189 | 0.78 | LMNA (0.63) | POLBLMNAALDH1A1SMN1; SMN2HTT | |
| SCHEMBL4073854 | 0.78 | LMNA (0.63) | LMNAALDH1A1SMN1; SMN2HTTMAPT | |
| SCHEMBL11798300 | 0.77 | LMNA (0.62) | LMNAALDH1A1TDP1SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120178086-A1 | REDUCTIVE RELEASE PROBES CONTAINING A CHEMOSELECTIVELY CLEAVABLE ALPHA-AZIDOETHER LINKER AND METHODS OF USE THEREOF | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2012-07-12 | — | — | US | claimed |
| WO-2011005821-A1 | REDUCTIVE RELEASE PROBES CONTAINING A CHEMOSELECTIVELY CLEAVABLE ALPHA-AZIDOETHER LINKER AND METHODS OF USE THEREOF | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2011-01-13 | — | — | WO | claimed |
| US-7745614-B2 | Universal linker compositions for the release or transfer of chemical agents from a polynucleotide | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2010-06-29 | — | — | US | claimed |
| US-20080124706-A1 | Nucleic acid probe, nucleic acid chip, method for detecting target nucleic acid, method for screening drug, apparatus for detecting target nucleic acid, and, gene diagnosis method | KYOTO UNIVERSITY (JP) | 2008-05-29 | — | — | US | claimed |
| EP-1717313-A1 | NUCLEIC ACID PROBE, NUCLEIC ACID CHIP, METHOD OF DETECTING TARGET NUCLEIC ACID, METHOD OF SCREENING DRUG, APPARATUS FOR DETECTING TARGET NUCLEIC ACID AND GENE DIAGNOSIS METHOD | Kyoto University (JP) | 2006-11-02 | — | — | EP | claimed |
| US-20060199192-A1 | Universal linker compositions for the release or transfer of chemical agents from a polynucleotide | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2006-09-07 | — | — | US | claimed |
| US-9422232-B2 | Reductive release probes containing a chemoselectively cleavable α-azidoether linker and methods of use thereof | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2016-08-23 | — | — | US | disclosed |
| US-9416155-B2 | Direct sensing of molecular species by polyfluors on a DNA backbone | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2016-08-16 | — | — | US | disclosed |
| US-20120309107-A1 | Direct Sensing of Molecular Species by Polyfluors on a DNA Backbone | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2012-12-06 | — | — | US | disclosed |
| US-20120178086-A1 | REDUCTIVE RELEASE PROBES CONTAINING A CHEMOSELECTIVELY CLEAVABLE ALPHA-AZIDOETHER LINKER AND METHODS OF USE THEREOF | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2012-07-12 | — | — | US | disclosed |
| WO-2011097437-A1 | DOUBLE DISPLACEMENT PROBES FOR NUCLEIC ACID DETECTION | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2011-08-11 | — | — | WO | disclosed |
| WO-2011081939-A1 | DIRECT SENSING OF MOLECULAR SPECIES BY POLYFLUORS ON A DNA BACKBONE | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2011-07-07 | — | — | WO | disclosed |
| WO-2011005821-A1 | REDUCTIVE RELEASE PROBES CONTAINING A CHEMOSELECTIVELY CLEAVABLE ALPHA-AZIDOETHER LINKER AND METHODS OF USE THEREOF | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2011-01-13 | — | — | WO | disclosed |
| US-7749699-B2 | Detection of chemical ligation using fluorescence quenching leaving groups | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2010-07-06 | — | — | US | disclosed |
| US-7745614-B2 | Universal linker compositions for the release or transfer of chemical agents from a polynucleotide | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2010-06-29 | — | — | US | disclosed |
| US-20060199192-A1 | Universal linker compositions for the release or transfer of chemical agents from a polynucleotide | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2006-09-07 | — | — | US | disclosed |
| EP-1543156-A4 | DETECTION OF CHEMICAL LIGATION USING FLUORESCENCE QUENCHING LEAVING GROUPS | UNIV LELAND STANFORD JUNIOR (US) | 2005-12-21 | — | — | EP | disclosed |
| EP-1543156-A2 | DETECTION OF CHEMICAL LIGATION USING FLUORESCENCE QUENCHING LEAVING GROUPS | The Board of Trustees of the Leland Stanford Junior University (US) | 2005-06-22 | — | — | EP | disclosed |
| US-20040259102-A1 | DETECTION OF CHEMICAL LIGATION USING FLUORESCENCE QUENCHING LEAVING GROUPS | STANFORD UNIVERSITY (US) | 2004-12-23 | — | — | US | disclosed |
| WO-2004010101-A2 | DETECTION OF CHEMICAL LIGATION USING FLUORESCENCE QUENCHING LEAVING GROUPS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2004-01-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120309107-A1 | Direct Sensing of Molecular Species by Polyfluors on a DNA Backbone | ERCC4, POLL, POLQ | POLB 19/4885CYP2D6 4335/4885LMNA 189/4885 |
| US-20060199192-A1 | Universal linker compositions for the release or transfer of chemical agents from a polynucleotide | ADAR, POLRMT, RNGTT | POLB 34/4885CYP2D6 4722/4885LMNA 207/4885 |
| US-20120178086-A1 | REDUCTIVE RELEASE PROBES CONTAINING A CHEMOSELECTIVELY CLEAVABLE ALPHA-AZIDOETHER LINKER AND METHODS OF USE THEREOF | CPSF1, CPSF7, CPSF6 | POLB 1071/4885CYP2D6 3782/4885LMNA 400/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.