Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9902470 | 0.86 | KDM4E (0.41) | GRM5FFAR2HCRTR1HCRTR2SLC6A2 | |
| SCHEMBL9902283 | 0.81 | KDM4E (0.35) | GRM5FFAR2HCRTR1HCRTR2SLC6A2 | |
| SCHEMBL16994484 | 0.81 | GRM5 (0.32) | GRM5 | |
| SCHEMBL16982326 | 0.81 | GRM5 (0.32) | GRM5 | |
| SCHEMBL9901900 | 0.78 | EPHX2 (0.40) | GAAKMT2A | |
| SCHEMBL9905759 | 0.77 | KCNQ3 (0.33) | KDM4EGAAKMT2A | |
| SCHEMBL9901421 | 0.77 | EPHX2 (0.36) | GAAKMT2A | |
| SCHEMBL9901577 | 0.76 | GAA (0.34) | HCRTR1HCRTR2KDM4EGAAKMT2A | |
| SCHEMBL9901787 | 0.74 | GAA (0.43) | CDK5KDM4EGAAKMT2A | |
| SCHEMBL9902718 | 0.74 | KDM4E (0.30) | KDM4EGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2649048-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | Radikal Therapeutics Inc. (US) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012077108-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | RADIKAL THERAPEUTICS INC. (US) | 2012-06-14 | — | — | WO | disclosed |