Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | IDH1 | O75874 | 4/20 | 0.34 |
| ▸ | IDH2 | P48735 | 2/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.31 |
| ▸ | APBA1 | Q02410 | 2/20 | 0.31 |
| ▸ | XPO1 | O14980 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9902283 | 0.87 | KDM4E (0.35) | GAAKMT2AKDM4EGRM5ALDH1A1 | |
| SCHEMBL9902516 | 0.79 | GAA (0.40) | GAAKMT2AKDM4EALDH1A1MEN1 | |
| SCHEMBL9902470 | 0.78 | KDM4E (0.41) | GAAKMT2AKDM4EGRM5ALDH1A1 | |
| SCHEMBL9902043 | 0.77 | KDM4E (0.39) | GAAKMT2AKDM4EGRM5 | |
| SCHEMBL9902558 | 0.75 | KDM4E (0.37) | GAAKMT2AKDM4EIDH1IDH2 | |
| SCHEMBL9902954 | 0.74 | ALDH1A1 (0.41) | GAAKMT2AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL9903032 | 0.74 | RECQL (0.37) | GAAKMT2AKDM4EALDH1A1MEN1 | |
| SCHEMBL9901665 | 0.73 | GAA (0.39) | GAAKMT2AKDM4EGRM5ALDH1A1 | |
| SCHEMBL9901731 | 0.72 | KDM4E (0.35) | GAAKMT2AKDM4E | |
| SCHEMBL16994486 | 0.69 | KDM4E (0.32) | GAAKMT2AKDM4EGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2649048-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | Radikal Therapeutics Inc. (US) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012077108-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | RADIKAL THERAPEUTICS INC. (US) | 2012-06-14 | — | — | WO | disclosed |