Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9902597 | 0.78 | GRIN2D (0.47) | TBXA2RTBXAS1ALDH1A1POLBTP53 | |
| SCHEMBL9902971 | 0.76 | ROCK2 (0.36) | ALDH1A1TP53LMNACYP1A2CYP2C19 | |
| SCHEMBL9901561 | 0.75 | GRIN2D (0.42) | ALDH1A1POLBTP53NPC1RAB9A | |
| SCHEMBL9902996 | 0.75 | MEN1 (0.46) | ALDH1A1PKMNPC1RAB9ALMNA | |
| SCHEMBL9902657 | 0.72 | ALDH1A1 (0.52) | ALDH1A1POLBEPHX2 | |
| SCHEMBL9901681 | 0.72 | KMT2A (0.39) | ALDH1A1POLBEPHX2TP53PKM | |
| SCHEMBL9901465 | 0.71 | MEN1 (0.43) | ALDH1A1PKMNPC1RAB9ALMNA | |
| SCHEMBL9903230 | 0.68 | ALDH1A1 (0.54) | ALDH1A1POLBEPHX2 | |
| SCHEMBL9902487 | 0.68 | ALDH1A1 (0.47) | ALDH1A1POLBEPHX2PKMNPC1 | |
| SCHEMBL2801166 | 0.67 | LMNA (0.53) | ALDH1A1POLBTP53PKMNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2649048-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | Radikal Therapeutics Inc. (US) | 2013-10-16 | — | — | EP | disclosed |
| CN-103347856-A | Multifunctional nitroxide derivatives and uses thereof | RADIKAL THERAPEUTICS INC | 2013-10-09 | — | — | CN | disclosed |
| WO-2012077108-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | RADIKAL THERAPEUTICS INC. (US) | 2012-06-14 | — | — | WO | disclosed |