Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9901790 | 0.85 | GAA (0.40) | EPHX2TSHRALDH1A1HTTKDM4E | |
| SCHEMBL9901580 | 0.85 | SIGMAR1 (0.40) | KMT2ATSHRGRIN2BALDH1A1CYP3A4 | |
| SCHEMBL9901676 | 0.73 | TSHR (0.40) | KMT2AEPHX2MEN1USP2TSHR | |
| SCHEMBL9902660 | 0.72 | TBXA2R (0.43) | EPHX2ALDH1A1NAMPTHPGDTP53 | |
| SCHEMBL16994485 | 0.70 | P2RX7 (0.43) | KMT2AEPHX2MEN1USP2TSHR | |
| SCHEMBL19668355 | 0.70 | P2RX7 (0.43) | KMT2AEPHX2MEN1USP2TSHR | |
| SCHEMBL9903246 | 0.70 | KDM4E (0.44) | KMT2AEPHX2TSHRALDH1A1HTT | |
| SCHEMBL18758199 | 0.70 | ALDH1A1 (0.62) | ALDH1A1HTTKDM4EHPGDMITF | |
| SCHEMBL16994510 | 0.68 | P2RX7 (0.44) | KMT2AEPHX2MEN1USP2TSHR | |
| SCHEMBL9902357 | 0.68 | P2RX7 (0.44) | KMT2AEPHX2MEN1USP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2649048-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | Radikal Therapeutics Inc. (US) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012077108-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | RADIKAL THERAPEUTICS INC. (US) | 2012-06-14 | — | — | WO | disclosed |