Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 8/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | FPR3 | P25089 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9901704 | 0.87 | EPHX2 (0.36) | L3MBTL1RAB9ASMN1; SMN2LMNANPC1 | |
| SCHEMBL9901421 | 0.87 | EPHX2 (0.36) | L3MBTL1RAB9ASMN1; SMN2KMT2ANPC1 | |
| SCHEMBL9901577 | 0.86 | GAA (0.34) | L3MBTL1KDM4ESMN1; SMN2KMT2ALMNA | |
| SCHEMBL9902509 | 0.85 | GAA (0.37) | TDP1L3MBTL1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL9901787 | 0.84 | GAA (0.43) | L3MBTL1KDM4EKMT2ALMNAALDH1A1 | |
| SCHEMBL9903261 | 0.84 | KDM4E (0.42) | OPRM1OPRD1TDP1L3MBTL1KDM4E | |
| SCHEMBL9901584 | 0.80 | HCRTR2 (0.35) | TDP1L3MBTL1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL9902706 | 0.79 | KCNQ3 (0.35) | KDM4EFPR2FPR3KMT2A | |
| SCHEMBL9905759 | 0.79 | KCNQ3 (0.33) | KDM4EKMT2A | |
| SCHEMBL9901445 | 0.79 | EPHX2 (0.33) | L3MBTL1RAB9ASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2649048-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | Radikal Therapeutics Inc. (US) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012077108-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | RADIKAL THERAPEUTICS INC. (US) | 2012-06-14 | — | — | WO | disclosed |