Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9901421 | 0.87 | EPHX2 (0.36) | EPHX2ALDH1A1SMN1; SMN2NPC1EPHX1 | |
| SCHEMBL9902746 | 0.87 | OPRM1 (0.37) | EPHX2LMNACHRNA7ALDH1A1SMN1; SMN2 | |
| SCHEMBL9901445 | 0.87 | EPHX2 (0.33) | EPHX2LMNAPOLBALDH1A1NPSR1 | |
| SCHEMBL9901577 | 0.86 | GAA (0.34) | EPHX2LMNAP2RX7POLBALDH1A1 | |
| SCHEMBL9903481 | 0.85 | KMT2A (0.38) | EPHX2LMNAALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL9901787 | 0.84 | GAA (0.43) | EPHX2LMNAALDH1A1EPHX1HTT | |
| SCHEMBL9902706 | 0.84 | KCNQ3 (0.35) | GAA | |
| SCHEMBL9901779 | 0.81 | SMARCA2 (0.39) | GAA | |
| SCHEMBL9901795 | 0.80 | P2RX7 (0.36) | EPHX2LMNAP2RX7ALDH1A1SMN1; SMN2 | |
| SCHEMBL9905759 | 0.79 | KCNQ3 (0.33) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2649048-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | Radikal Therapeutics Inc. (US) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012077108-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | RADIKAL THERAPEUTICS INC. (US) | 2012-06-14 | — | — | WO | disclosed |