Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9902746 | 0.86 | OPRM1 (0.37) | KDM4EKMT2ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL9901787 | 0.86 | GAA (0.43) | GAAKDM4EKMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL9901704 | 0.86 | EPHX2 (0.36) | GAASMN1; SMN2L3MBTL1ALDH1A1EPHX2 | |
| SCHEMBL9901421 | 0.86 | EPHX2 (0.36) | GAAKMT2ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL9901676 | 0.85 | TSHR (0.40) | KDM4EKMT2AALDH1A1EPHX2POLB | |
| SCHEMBL9901900 | 0.85 | EPHX2 (0.40) | GAAKMT2ASMN1; SMN2ALDH1A1EPHX2 | |
| SCHEMBL9902509 | 0.85 | GAA (0.37) | GAAKDM4EKMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL9903481 | 0.85 | KMT2A (0.38) | KMT2ASMN1; SMN2ALDH1A1EPHX2TSHR | |
| SCHEMBL9901795 | 0.82 | P2RX7 (0.36) | GAAKDM4EKMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL9901584 | 0.82 | HCRTR2 (0.35) | GAAKDM4EKMT2ASMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2649048-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | Radikal Therapeutics Inc. (US) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012077108-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | RADIKAL THERAPEUTICS INC. (US) | 2012-06-14 | — | — | WO | disclosed |