Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 7/20 | 0.37 |
| ▸ | FPR3 | P25089 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9902365 | 0.84 | KMT2A (0.39) | KDM4EGAAKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL9902746 | 0.84 | OPRM1 (0.37) | KDM4EKMT2ARAB9ASMN1; SMN2MEN1 | |
| SCHEMBL9903243 | 0.83 | KDM4E (0.58) | KDM4EGAAKMT2ACA1CA2 | |
| SCHEMBL9903032 | 0.78 | RECQL (0.37) | KDM4EGAAKMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL9902803 | 0.78 | GAA (0.41) | KDM4EGAAKMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL9902154 | 0.77 | KDM4E (0.38) | KDM4EGAAKMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL9901731 | 0.71 | KDM4E (0.35) | KDM4EGAAKMT2AOPRM1 | |
| SCHEMBL9903262 | 0.71 | GRIN2D (0.44) | KDM4EGAAKMT2ACA1CA2 | |
| SCHEMBL9901606 | 0.70 | FPR2 (0.35) | KDM4EGAAKMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL9901609 | 0.70 | FPR2 (0.35) | KDM4EGAAKMT2ARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2649048-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | Radikal Therapeutics Inc. (US) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012077108-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | RADIKAL THERAPEUTICS INC. (US) | 2012-06-14 | — | — | WO | disclosed |