Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 2/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9901795 | 0.85 | P2RX7 (0.36) | HCRTR2HCRTR1L3MBTL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL9901577 | 0.82 | GAA (0.34) | HCRTR2HCRTR1L3MBTL1SMN1; SMN2POLB | |
| SCHEMBL9902746 | 0.80 | OPRM1 (0.37) | L3MBTL1SMN1; SMN2ALDH1A1KMT2AKDM4E | |
| SCHEMBL17271393 | 0.79 | HCRTR2 (0.32) | HCRTR2HCRTR1L3MBTL1SMN1; SMN2POLB | |
| SCHEMBL17271392 | 0.79 | HCRTR2 (0.32) | HCRTR2HCRTR1L3MBTL1SMN1; SMN2POLB | |
| SCHEMBL9902509 | 0.78 | GAA (0.37) | HCRTR2HCRTR1L3MBTL1SMN1; SMN2CASP6 | |
| SCHEMBL9901787 | 0.74 | GAA (0.43) | L3MBTL1ALDH1A1CYP3A4KMT2AGAA | |
| SCHEMBL9901421 | 0.74 | EPHX2 (0.36) | L3MBTL1SMN1; SMN2ALDH1A1KMT2AGAA | |
| SCHEMBL9901704 | 0.74 | EPHX2 (0.36) | L3MBTL1SMN1; SMN2POLBALDH1A1CYP2C19 | |
| SCHEMBL9903481 | 0.73 | KMT2A (0.38) | SMN1; SMN2ALDH1A1CYP3A4CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2649048-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | Radikal Therapeutics Inc. (US) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012077108-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | RADIKAL THERAPEUTICS INC. (US) | 2012-06-14 | — | — | WO | disclosed |