Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.34 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | PRKACA | P17612 | 1/20 | 0.32 |
| ▸ | FRK | P42685 | 1/20 | 0.32 |
| ▸ | GSK3A | P49840 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | NEK4 | P51957 | 1/20 | 0.32 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.32 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9901577 | 0.86 | GAA (0.34) | GAAKDM4EALDH1A1EPHX2KMT2A | |
| SCHEMBL9901676 | 0.85 | TSHR (0.40) | KDM4EALDH1A1EPHX2KMT2ATSHR | |
| SCHEMBL9901704 | 0.84 | EPHX2 (0.36) | GAAALDH1A1EPHX2EPHX1L3MBTL1 | |
| SCHEMBL9902746 | 0.84 | OPRM1 (0.37) | KDM4EALDH1A1EPHX2KMT2AEPHX1 | |
| SCHEMBL9901421 | 0.84 | EPHX2 (0.36) | GAAALDH1A1EPHX2KMT2AEPHX1 | |
| SCHEMBL9903243 | 0.84 | KDM4E (0.58) | GAAKDM4EALDH1A1ALOX15EPHX2 | |
| SCHEMBL9901779 | 0.83 | SMARCA2 (0.39) | GAAKDM4EKMT2A | |
| SCHEMBL9902706 | 0.79 | KCNQ3 (0.35) | GAAKDM4EKMT2A | |
| SCHEMBL9905759 | 0.79 | KCNQ3 (0.33) | GAAKDM4EKMT2A | |
| SCHEMBL9901445 | 0.79 | EPHX2 (0.33) | GAAALDH1A1EPHX2KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2649048-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | Radikal Therapeutics Inc. (US) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012077108-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | RADIKAL THERAPEUTICS INC. (US) | 2012-06-14 | — | — | WO | disclosed |