Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13555517 | 0.88 | CYP1A2 (0.40) | CYP1A2CYP3A4CYP2C19RAB9ANPC1 | |
| SCHEMBL17124327 | 0.86 | CYP1A2 (0.40) | CYP1A2CYP3A4CYP2C19RAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL13386361 | 0.85 | CYP1A2 (0.38) | CYP1A2CYP3A4CYP2C19RAB9ANPC1 | |
| SCHEMBL7546969 | 0.80 | POLB (0.49) | RAB9AMAOBALDH1A1LMNAMAOA | |
| SCHEMBL17128901 | 0.79 | MAOB (0.41) | CYP2C19RAB9AMAOBALDH1A1SMN1; SMN2 | |
| SCHEMBL12949658 | 0.79 | CRHR1 (0.40) | CYP1A2CYP3A4CYP2C19ALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL6993015 | 0.79 | POLB (0.47) | RAB9AMAOBALDH1A1LMNAMAOA | |
| SCHEMBL18662703 | 0.77 | CRHR1 (0.41) | CYP3A4CYP2C19ALDH1A1POLBGAA | |
| SCHEMBL7554482 | 0.73 | MMP1 (0.40) | CYP2C19MAOBMAOAPOLBTYR | |
| Hydrochloric Acid SCHEMBL6989988 | 0.71 | MMP1 (0.39) | CYP2C19MAOBMAOAPOLBTYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9938240-B2 | Fluorinated derivatives of 3-hydroxypyridin-4-ones | APOTEX INC. (CA) | 2018-04-10 | — | — | US | disclosed |
| US-9938240-B2 | Fluorinated derivatives of 3-hydroxypyridin-4-ones | APOTEX INC. (CA) | 2018-04-10 | — | — | US | disclosed |
| US-9938240-B2 | Fluorinated derivatives of 3-hydroxypyridin-4-ones | APOTEX INC. (CA) | 2018-04-10 | — | — | US | disclosed |
| US-20170247329-A1 | \"Fluorinated Derivatives of 3-Hydroxypyridin-4-Ones\ | APOTEX TECHNOLOGIES INC. (CA) | 2017-08-31 | — | — | US | disclosed |
| US-20170247329-A1 | \"Fluorinated Derivatives of 3-Hydroxypyridin-4-Ones\ | APOTEX TECHNOLOGIES INC. (CA) | 2017-08-31 | — | — | US | disclosed |
| US-20170247329-A1 | \"Fluorinated Derivatives of 3-Hydroxypyridin-4-Ones\ | APOTEX TECHNOLOGIES INC. (CA) | 2017-08-31 | — | — | US | disclosed |
| US-20170088518-A1 | Fluorinated Derivatives of 3-Hydroxypyridin-4-Ones | THE BANK OF NOVA SCOTIA (CA) | 2017-03-30 | — | — | US | disclosed |
| US-20170088518-A1 | Fluorinated Derivatives of 3-Hydroxypyridin-4-Ones | THE BANK OF NOVA SCOTIA (CA) | 2017-03-30 | — | — | US | disclosed |
| US-20170088518-A1 | Fluorinated Derivatives of 3-Hydroxypyridin-4-Ones | THE BANK OF NOVA SCOTIA (CA) | 2017-03-30 | — | — | US | disclosed |
| US-9550733-B2 | Fluorinated derivatives of 3-hydroxypyridin-4-ones | APOTEX TECHNOLOGIES INC. (CA) | 2017-01-24 | — | — | US | disclosed |
| US-20150274665-A1 | FLUORINATED DERIVATIVES OF 3-HYDROXYPYRIDIN-4-ONES | FLORIDA TURBINE TECHNOLOGIES, INC. | 2015-10-01 | — | — | US | disclosed |
| US-9073865-B2 | Fluorinated derivates of 3-hydroxypyridin-4-ones | APOTEX TECHNOLOGIES INC. (CA) | 2015-07-07 | — | — | US | disclosed |
| US-9073865-B2 | Fluorinated derivates of 3-hydroxypyridin-4-ones | APOTEX TECHNOLOGIES INC. (CA) | 2015-07-07 | — | — | US | disclosed |
| US-9073865-B2 | Fluorinated derivates of 3-hydroxypyridin-4-ones | APOTEX TECHNOLOGIES INC. (CA) | 2015-07-07 | — | — | US | disclosed |
| EP-2448922-B1 | FLUORINATED DERIVATIVES OF 3-HYDROXYPYRIDIN-4-ONES | APOTEX TECHNOLOGIES INC (CA) | 2014-08-20 | — | — | EP | disclosed |
| EP-2448922-B1 | FLUORINATED DERIVATIVES OF 3-HYDROXYPYRIDIN-4-ONES | APOTEX TECHNOLOGIES INC (CA) | 2014-08-20 | — | — | EP | disclosed |
| US-20120270882-A1 | FLUORINATED DERIVATES OF 3-HYDROXYPYRIDIN-4-ONES | APOTEX TECHNOLOGIES INC. (CA) | 2012-10-25 | — | — | US | disclosed |
| EP-2448922-A1 | FLUORINATED DERIVATIVES OF 3-HYDROXYPYRIDIN-4-ONES | Apotex Technologies Inc. (CA) | 2012-05-09 | — | — | EP | disclosed |
| WO-2011000104-A1 | FLUORINATED DERIVATIVES OF 3-HYDROXYPYRIDIN-4-ONES | APOTEX TECHNOLOGIES INC. (CA) | 2011-01-06 | — | — | WO | disclosed |
| WO-2011000104-A1 | FLUORINATED DERIVATIVES OF 3-HYDROXYPYRIDIN-4-ONES | APOTEX TECHNOLOGIES INC. (CA) | 2011-01-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120270882-A1 | FLUORINATED DERIVATES OF 3-HYDROXYPYRIDIN-4-ONES | FH, FECH, FTH1 | CYP1A2 199/4885CYP3A4 310/4885CYP2C19 64/4885 |
| US-20170088518-A1 | Fluorinated Derivatives of 3-Hydroxypyridin-4-Ones | FH, FECH, FPGS | CYP1A2 303/4885CYP3A4 420/4885CYP2C19 109/4885 |
| US-20170247329-A1 | \"Fluorinated Derivatives of 3-Hydroxypyridin-4-Ones\ | FH, FECH, FPGS | CYP1A2 307/4885CYP3A4 488/4885CYP2C19 114/4885 |
| US-20150274665-A1 | FLUORINATED DERIVATIVES OF 3-HYDROXYPYRIDIN-4-ONES | FH, FECH, TFRC | CYP1A2 253/4885CYP3A4 405/4885CYP2C19 80/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.