Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | S100B | P04271 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15651320 | 0.83 | LGMN (0.49) | KEAP1CYP3A4TSHRPIK3CAADRA2C | |
| SCHEMBL23843550 | 0.79 | ADRB1 (0.69) | TSHRGAAALDH1A1MEN1KMT2A | |
| SCHEMBL31172356 | 0.79 | KEAP1 (0.67) | KEAP1ADRA2CGAAALDH1A1MEN1 | |
| SCHEMBL29938274 | 0.79 | KEAP1 (0.95) | KEAP1ADRA2CGAAALDH1A1MEN1 | |
| SCHEMBL484010 | 0.79 | KEAP1 (0.95) | KEAP1ADRA2CGAAALDH1A1MEN1 | |
| SCHEMBL20436326 | 0.78 | KEAP1 (0.59) | KEAP1ADRA2CGAAALDH1A1MEN1 | |
| SCHEMBL3312656 | 0.78 | ALDH1A1 (0.72) | TSHRGAAALDH1A1MEN1KMT2A | |
| SCHEMBL9065218 | 0.78 | LMNA (0.68) | TSHRGAAALDH1A1MEN1KMT2A | |
| SCHEMBL31172297 | 0.78 | KEAP1 (0.70) | KEAP1ADRA2CGAAALDH1A1MEN1 | |
| SCHEMBL15365564 | 0.78 | KEAP1 (0.70) | KEAP1ADRA2CGAAALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014118092-A2 | DYE COMPOSITION COMPRISING AT LEAST ONE PARTICULAR LIPOPHILIC META-PHENYLENEDIAMINE COUPLER IN A MEDIUM RICH IN FATTY SUBSTANCES, PROCESSES AND DEVICES | L'OREAL (FR) | 2014-08-07 | — | — | WO | disclosed |
| WO-2011072241-A9 | 4-OXO-1H-QUINOLINE-3-CARBOXAMIDES AS MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2012-06-14 | — | — | WO | disclosed |